Marshall J A, Salamone S, Yuen L, Catton M G, Wright J P
Victorian Infectious Diseases Reference Laboratory, Carlton South, Australia.
Pathology. 2001 Feb;33(1):50-2.
We report the case of an elderly woman excreting high levels (about 5 x 10(5) virions per gram of faeces) of Norwalk-like virus (NLV) in the absence of any clinical symptoms of gastroenteritis. Analysis by reverse transcription, polymerase chain reaction and DNA sequencing was carried out on a 342-nucleotide region of open reading frame 1. This indicated that the NLV belonged to genogroup 2 and was more closely related to the Camberwell subgroup, the most common circulating in southeast Australia at present, than to the Norwalk and Mexico viruses.
我们报告了一例老年女性病例，该女性在没有任何肠胃炎临床症状的情况下，排出高水平（约每克粪便含5×10⁵个病毒粒子）的诺如病毒（NLV）。对开放阅读框1的一个342个核苷酸区域进行了逆转录、聚合酶链反应和DNA测序分析。结果表明，该NLV属于基因群2，与坎伯韦尔亚组的关系比与诺沃克病毒和墨西哥病毒的关系更为密切，坎伯韦尔亚组是目前在澳大利亚东南部最常见的流行毒株。
