Tomich P K, An F Y, Damle S P, Clewell D B
Antimicrob Agents Chemother. 1979 Jun;15(6):828-30. doi: 10.1128/AAC.15.6.828.
Streptococcus faecalis subsp. zymogenes strain DS16 was found to harbor two plasmids, designated pAD1 (35 megadaltons) and pAD2 (15 megadaltons). pAD1 is transmissible and determines a hemolysin-bacteriocin, whereas pAD2 is non-conjugative and determines resistance to erythromycin, streptomycin, and kanamycin. pAD2 could be mobilized by pAD1, but usually involved formation of a pAD1-pAD2 cointegrate.
粪肠球菌发酵亚种菌株DS16被发现含有两个质粒,分别命名为pAD1(35兆道尔顿)和pAD2(15兆道尔顿)。pAD1是可转移的,并决定一种溶血素-细菌素,而pAD2是非接合性的,并决定对红霉素、链霉素和卡那霉素的抗性。pAD2可被pAD1动员,但通常涉及形成pAD1-pAD2共整合体。