Bosworth H B, Siegler I C, Olsen M K, Brummett B H, Barefoot J C, Williams R B, Clapp-Channing N E, Mark D B
Health Services Research and Development, Durham VAMC, NC 27705, USA.
Qual Life Res. 2000;9(7):829-39. doi: 10.1023/a:1008960308011.
The relationship between perceived social support and domain-specific health-related quality of life (HRQOL) was examined in a sample of cardiac catheterization patients after considering age, gender, race, education, and coronary artery disease (CAD) severity. Data was collected on 4,278 cardiac catheterization patients (63% males) and included 1,215 patients with non-significant CAD and 3,063 patients who had significant CAD ( > or = 75% stenosis of at least one major coronary artery). Among the patients with significant CAD, 2,721 were classified as low disease severity and 342 were considered high disease severity. Regression models indicated that a lack of social support was associated with significantly lower levels of HRQOL across all eight SF-36 HRQOL domains after considering disease severity and other demographic factors. The models also indicated that social support and other relevant variables interacted across various HRQOL domains. Physical function and physical role function were lower with age, whereas mental health, emotional role function, and vitality were higher with age. Females reported lower HRQOL than males across all domains. Minority patients reported lower levels of HRQOL than white patients across four domains. Increased disease severity was related to lower levels among four of the eight HRQOL domains. The observed interactions of social support with minority status, disease severity, and education suggest that a subset of individuals may suffer lower levels of HRQOL. These individuals may subsequently require the greatest degree of care and potentially benefit most from intervention.
在考虑年龄、性别、种族、教育程度和冠状动脉疾病（CAD）严重程度后，对一组心脏导管插入术患者感知到的社会支持与特定领域的健康相关生活质量（HRQOL）之间的关系进行了研究。收集了4278名心脏导管插入术患者的数据（63%为男性），其中包括1215名CAD不显著的患者和3063名CAD显著的患者（至少一条主要冠状动脉狭窄≥75%）。在CAD显著的患者中，2721名被归类为疾病严重程度低，342名被认为疾病严重程度高。回归模型表明，在考虑疾病严重程度和其他人口统计学因素后，缺乏社会支持与所有八个SF - 36 HRQOL领域的HRQOL水平显著降低相关。模型还表明，社会支持和其他相关变量在各个HRQOL领域相互作用。身体功能和身体角色功能随年龄增长而降低，而心理健康、情感角色功能和活力随年龄增长而升高。在所有领域中，女性报告的HRQOL低于男性。在四个领域中，少数族裔患者报告的HRQOL水平低于白人患者。疾病严重程度增加与八个HRQOL领域中的四个领域水平降低有关。观察到的社会支持与少数族裔地位、疾病严重程度和教育程度之间的相互作用表明，一部分个体可能会有较低的HRQOL水平。这些个体随后可能需要最大程度的护理，并可能从干预中获益最多。
