Nakanishi N, Yoshida H, Nagano K, Kawashimo H, Nakamura K, Tatara K
Department of Social and Environmental Medicine, Course of Social Medicine, Osaka University Graduate School of Medicine F2, 2-2 Yamada-oka, Suita-shi, Osaka 565-0871, Japan.
J Epidemiol Community Health. 2001 May;55(5):316-22. doi: 10.1136/jech.55.5.316.
To evaluate the association of long working hours with the risk for hypertension.
A five year prospective cohort study.
Work site in Osaka, Japan.
941 hypertension free Japanese male white collar workers aged 35-54 years were prospectively examined by serial annual health examinations. Men in whom borderline hypertension and hypertension were found during repeated surveys were defined as incidental cases of borderline hypertension and hypertension.
336 and 88 men developed hypertension above the borderline level and definite hypertension during the 3940 and 4531 person years, respectively. After controlling for potential predictors of hypertension, the relative risk for hypertension above the borderline level, compared with those who worked < 8.0 hours per day, was 0.63 (95% confidence intervals (CI): 0.43, 0.91) for those who worked 10.0-10.9 hours per day and 0.48 (95% CI: 0.31, 0.74) for those who worked > or = 11.0 hours per day. The relative risk for definite hypertension, compared with those who worked < 8.0 hours per day, was 0.33 (95% CI: 0.11, 0.95) for those who worked > or = 11.0 hours per day. The multivariate adjusted slopes of diastolic blood pressure (DBP) and mean arterial blood pressure (MABP) during five years of follow up decreased as working hours per day increased. From the multiple regression analyses, working hours per day remained as an independent negative factor for the slopes of systolic blood pressure, DBP, and MABP.
These results indicate that long working hours are negatively associated with the risk for hypertension in Japanese male white collar workers.
评估长时间工作与高血压风险之间的关联。
一项为期五年的前瞻性队列研究。
日本大阪的工作场所。
941名年龄在35 - 54岁之间、无高血压的日本男性白领工人，通过每年的系列健康检查进行前瞻性观察。在重复调查中发现临界高血压和高血压的男性被定义为临界高血压和高血压的偶发病例。
在3940和4531人年期间，分别有336名和88名男性发展为临界以上高血压和确诊高血压。在控制了高血压的潜在预测因素后，与每天工作<8.0小时的人相比，每天工作10.0 - 10.9小时的人临界以上高血压的相对风险为0.63（95%置信区间（CI）：0.43，0.91），每天工作≥11.0小时的人相对风险为0.48（95%CI：0.31，0.74）。与每天工作<8.0小时的人相比，每天工作≥11.0小时的人确诊高血压的相对风险为0.33（95%CI：0.11，0.95）。在五年随访期间，舒张压（DBP）和平均动脉压（MABP）的多变量调整斜率随着每天工作时间的增加而降低。从多元回归分析来看，每天工作时间仍然是收缩压、DBP和MABP斜率的独立负性因素。
这些结果表明，长时间工作与日本男性白领工人的高血压风险呈负相关。
