Dalkýz M, Ozcan A, Yapar M, Gökay N, Yüncü M
Department of Prosthetic Dentistry, Gülhane Military Medical Academy, Ankara, Turkey.
Implant Dent. 2000;9(3):226-35. doi: 10.1097/00008505-200009030-00008.
Studies concerning natural and synthetic graft materials that have been used in different medical procedures have focused on freeze-dried bone, coral, hydroxylapatite, and tricalcium phosphate. This study histologically investigates the effects of these materials on the healing of bone defects. The experiments were performed on 30 albino rabbits. Cavities were drilled in the posterior right tibias of rabbits and were filled with coral, freeze-dried bone, hydroxylapatite, or calcium hydroxide. One cavity was left unfilled as a control. The bone in which the materials were implanted was excised at 7, 15, 30, 45, and 60 days. After the histological staining procedures, the prepared materials were observed using a light microscope. Although all materials showed good bone remodeling at the end of 60 days, coral and hydroxylapatite materials could be seen in the bone structure. The most effective materials within bone defect improvement were freeze-dried bone and calcium hydroxide.
关于已用于不同医疗程序的天然和合成移植材料的研究主要集中在冻干骨、珊瑚、羟基磷灰石和磷酸三钙上。本研究通过组织学方法调查这些材料对骨缺损愈合的影响。实验在30只白化兔身上进行。在兔右后胫骨上钻孔，并分别填充珊瑚、冻干骨、羟基磷灰石或氢氧化钙。留一个未填充的孔作为对照。在第7、15、30、45和60天切除植入材料的骨头。经过组织学染色程序后，使用光学显微镜观察制备的材料。尽管所有材料在60天结束时都显示出良好的骨重塑，但在骨结构中可以看到珊瑚和羟基磷灰石材料。在改善骨缺损方面最有效的材料是冻干骨和氢氧化钙。
