Canfield L M, Kaminsky R G, Taren D L, Shaw E, Sander J K
Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, AZ 85724.
Eur J Nutr. 2001 Feb;40(1):30-8. doi: 10.1007/pl00007383.
Despite vitamin A supplementation programs, vitamin A deficiency in children remains a public health concern in Honduras.
We investigated the effectiveness of short-term dietary supplementation of mothers with red palm oil as a strategy for improving the vitamin A status of the mother-infant dyad.
Lactating mothers in Colonia Los Pinos, a barrio of Tegucigalpa, Honduras, consumed a total of 90-mg beta-carotene as red palm oil (n = 32) supplements (n = 36) or placebo (n = 18) in six equal doses over 10 days. Carotenoids and retinol in maternal and infant serum, and breastmilk carotenoids and retinol were measured before and after supplementation. Maternal diet was evaluated by 24-hour recall.
Maternal serum alpha-carotene and beta-carotene concentrations were increased 2 fold by palm oil compared with 1.2 fold by beta-carotene supplements. Changes were significantly different in infant serum alpha-carotene but not beta-carotene among the three experimental groups. Increases in breastmilk beta-carotene were greater for the palm oil group (2.5 fold) than for the beta-carotene supplement group (1.6 fold) and increases in milk alpha-carotene concentrations (3.2 fold) were slightly greater than those of beta-carotene. There were also small but significant changes among groups in breastmilk lutein and lycopene. Breastmilk retinol was not significantly different among the groups over the treatment period.
Red palm oil in the maternal diet increases provitamin A carotenoids in breastmilk and serum of the mother-infant dyad. The use of dietary red palm oil to improve the vitamin A status of this population should be further investigated.
尽管实施了维生素A补充计划，但在洪都拉斯，儿童维生素A缺乏仍然是一个公共卫生问题。
我们调查了短期向母亲膳食中补充红棕榈油作为改善母婴维生素A状况策略的有效性。
在洪都拉斯特古西加尔巴一个名为科洛尼亚洛斯皮诺斯的街区，哺乳期母亲在10天内分六等份服用了共90毫克作为红棕榈油的β-胡萝卜素（n = 32）补充剂（n = 36）或安慰剂（n = 18）。在补充前后测量母婴血清中的类胡萝卜素和视黄醇，以及母乳中的类胡萝卜素和视黄醇。通过24小时回忆法评估母亲的饮食。
与β-胡萝卜素补充剂使母亲血清α-胡萝卜素和β-胡萝卜素浓度增加1.2倍相比，棕榈油使其增加了2倍。在三个实验组中，婴儿血清α-胡萝卜素发生了显著变化，但β-胡萝卜素没有。棕榈油组母乳中β-胡萝卜素的增加幅度（2.5倍）大于β-胡萝卜素补充剂组（1.6倍），母乳中α-胡萝卜素浓度的增加幅度（3.2倍）略大于β-胡萝卜素。母乳中叶黄素和番茄红素在各组之间也有微小但显著的变化。在治疗期间，各组母乳中的视黄醇没有显著差异。
母亲饮食中的红棕榈油会增加母婴二元组母乳和血清中的维生素A原类胡萝卜素。应进一步研究使用膳食红棕榈油来改善该人群维生素A状况的情况。
