Henkelman R M, Stanisz G J, Graham S J
Department of Medical Biophysics University of Toronto, Toronto, Canada.
NMR Biomed. 2001 Apr;14(2):57-64. doi: 10.1002/nbm.683.
This review describes magnetization transfer (MT) contrast in magnetic resonance imaging. A qualitative description of how MT works is provided along with experimental evidence that leads to a quantitative model for MT in tissues. The implementation of MT saturation in imaging sequences and the interpretation of the MT-induced signal change in terms of exchange processes and direct effects are presented. Finally, highlights of clinical uses of MT are outlined and future directions for investigation proposed.
本综述描述了磁共振成像中的磁化传递（MT）对比。文中提供了MT工作原理的定性描述以及能导出组织中MT定量模型的实验证据。介绍了成像序列中MT饱和的实现方式以及从交换过程和直接效应方面对MT诱导的信号变化的解释。最后，概述了MT临床应用的要点并提出了未来的研究方向。
