Toledo T K, DiPalma J A
Division of Gastroenterology, University of South Alabama College of Medicine, Mobile, Alabama 36693, USA.
Aliment Pharmacol Ther. 2001 May;15(5):605-11. doi: 10.1046/j.1365-2036.2001.00966.x.
Adequate cleansing is essential for reliable diagnostic and surgical colon procedures. Accuracy and safety depend on good preparation. Patient compliance is enhanced by simplicity and well-tolerated methods. Several methods are available. Diet and cathartic regimens utilize clear liquids or diets designed to leave a minimal colonic residue. Laxatives, cathartics and enemas are employed. Gut lavage solutions are osmotically balanced electrolyte lavage products. Oral sodium phosphate solutions and tablets are available and are attractive because of good efficacy with a small volume of administration. For colonoscopy and colon surgery preparation, these methods have been proven safe and effective. For barium enema X-ray, lavage requires an adjunctive agent such as bisacodyl to enhance barium coating. Overall, all regimens are well-tolerated. This review discusses the development and clinical experience with various colon cleansing regimens.
充分清洁对于可靠的结肠诊断和外科手术程序至关重要。准确性和安全性取决于良好的准备工作。简单且耐受性良好的方法可提高患者的依从性。有多种方法可供选择。饮食和泻药方案采用清液或旨在使结肠残留最少的饮食。使用泻药、泻剂和灌肠剂。肠道灌洗溶液是渗透平衡的电解质灌洗产品。口服磷酸钠溶液和片剂可供使用,且因其给药量小但疗效良好而颇具吸引力。对于结肠镜检查和结肠手术的准备,这些方法已被证明是安全有效的。对于钡剂灌肠X线检查,灌洗需要一种辅助剂,如比沙可啶,以增强钡剂涂层。总体而言,所有方案的耐受性都良好。本综述讨论了各种结肠清洁方案的发展和临床经验。