Guzmán J, Esmail R, Karjalainen K, Malmivaara A, Irvin E, Bombardier C
Institute for Work and Health, Toronto, Canada M4W 1E6.
BMJ. 2001 Jun 23;322(7301):1511-6. doi: 10.1136/bmj.322.7301.1511.
To assess the effect of multidisciplinary biopsychosocial rehabilitation on clinically relevant outcomes in patients with chronic low back pain.
Systematic literature review of randomised controlled trials.
A total of 1964 patients with disabling low back pain for more than three months.
Pain, function, employment, quality of life, and global assessments.
Ten trials reported on a total of 12 randomised comparisons of multidisciplinary treatment and a control condition. There was strong evidence that intensive multidisciplinary biopsychosocial rehabilitation with functional restoration improves function when compared with inpatient or outpatient non-multidisciplinary treatments. There was moderate evidence that intensive multidisciplinary biopsychosocial rehabilitation with functional restoration reduces pain when compared with outpatient non-multidisciplinary rehabilitation or usual care. There was contradictory evidence regarding vocational outcomes of intensive multidisciplinary biopsychosocial intervention. Some trials reported improvements in work readiness, but others showed no significant reduction in sickness leaves. Less intensive outpatient psychophysical treatments did not improve pain, function, or vocational outcomes when compared with non-multidisciplinary outpatient therapy or usual care. Few trials reported effects on quality of life or global assessments.
The reviewed trials provide evidence that intensive multidisciplinary biopsychosocial rehabilitation with functional restoration reduces pain and improves function in patients with chronic low back pain. Less intensive interventions did not show improvements in clinically relevant outcomes.
评估多学科生物心理社会康复对慢性下腰痛患者临床相关结局的影响。
对随机对照试验进行系统文献综述。
共有1964例致残性下腰痛超过三个月的患者。
疼痛、功能、就业、生活质量和整体评估。
10项试验报告了总共12项多学科治疗与对照条件的随机比较。有强有力的证据表明,与住院或门诊非多学科治疗相比,强化的多学科生物心理社会康复与功能恢复可改善功能。有中等证据表明,与门诊非多学科康复或常规护理相比,强化的多学科生物心理社会康复与功能恢复可减轻疼痛。关于强化多学科生物心理社会干预的职业结局存在相互矛盾的证据。一些试验报告工作准备情况有所改善,但其他试验表明病假天数没有显著减少。与非多学科门诊治疗或常规护理相比,强度较低的门诊心理物理治疗并未改善疼痛、功能或职业结局。很少有试验报告对生活质量或整体评估有影响。
所综述的试验提供了证据,表明强化的多学科生物心理社会康复与功能恢复可减轻慢性下腰痛患者的疼痛并改善其功能。强度较低的干预措施在临床相关结局方面未显示出改善。