Serrano R, Rodriguez-Navarro A
Instituto de Biología Molecular y Celular de Plantas Universidad Politécnica de Valencia-C.S.I.C., Camino de Vera, 46022, Valencia, Spain.
Curr Opin Cell Biol. 2001 Aug;13(4):399-404. doi: 10.1016/s0955-0674(00)00227-1.
Recent progress has been made in the characterization of cation transporters that maintain ion homeostasis during salt stress in plants. Sodium-proton antiporters at the vacuolar (NHX1) and plasma membrane (SOS1) have been identified in Arabidopsis. SOS1 is regulated by the calcium-activated protein kinase complex SOS2-SOS3. In yeast, a transcription repressor, Sko1, mediates regulation of the sodium-pump ENA1 gene by the Hog1 MAP kinase. The recent visualization at the atomic level of the inhibitory site of sodium in the known target Hal2 has helped identify the interactions determining Na(+) toxicity.
在植物应对盐胁迫时维持离子稳态的阳离子转运体的特性研究方面已取得了新进展。拟南芥中已鉴定出液泡(NHX1)和质膜(SOS1)上的钠-质子反向转运体。SOS1受钙激活蛋白激酶复合体SOS2-SOS3调控。在酵母中,转录抑制因子Sko1介导Hog1丝裂原活化蛋白激酶对钠泵ENA1基因的调控。最近在原子水平上对已知靶点Hal2中钠抑制位点的可视化,有助于确定决定Na(+)毒性的相互作用。