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猴子中的麻疹:一项流行病学研究。

Measles in monkeys: an epidemiological study.

作者信息

MacArthur J A, Mann P G, Oreffo V, Scott G B

出版信息

J Hyg (Lond). 1979 Oct;83(2):207-12. doi: 10.1017/s0022172400025985.

Abstract

This study describes aspects of measles in non-human primates. Monkeys infected before importation are shown to produce non-immune offspring in captivity in England. The high antibody titres found in most recently imported monkeys decline slowly during captivity in England. While measles is often fatal to monkeys, we have described an outbreak in which a number of symptomless infections occurred. Histological examination of fatal cases produced evidence of infection in the wall of the urinary bladder in one monkey. The close similarity between measles in humans and monkeys has been confirmed. It is considered that the study of infection among the latter may have significance for the former.

摘要

本研究描述了非人灵长类动物中的麻疹情况。研究表明,在进口前感染的猴子在英国圈养期间会产出无免疫力的后代。最近进口的猴子中发现的高抗体滴度在英国圈养期间会缓慢下降。虽然麻疹通常对猴子是致命的,但我们描述了一次疫情,其中出现了一些无症状感染病例。对死亡病例的组织学检查发现,一只猴子的膀胱壁有感染迹象。人类麻疹与猴子麻疹之间的密切相似性得到了证实。人们认为,对后者感染情况的研究可能对前者具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1225/2129890/b043a2b668a8/jhyg00044-0019-a.jpg

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