Xiang T, Xiong Q B, Ketut A I, Tezuka Y, Nagaoka T, Wu L J, Kadota S
Department of Natural Medicine, Shenyang Pharmaceutical University, Shenyang, People's Republic of China.
Planta Med. 2001 Jun;67(4):322-5. doi: 10.1055/s-2001-14337.
13 quinic acid derivatives along with caffeic acid, methyl caffeate, myo-inositol, bis[5-formylfurfuryl] ether and 6,7-dihydroxycoumarin were isolated from the ethanol extract of the flower buds of Lonicera bournei Hemsl., among which 8 compounds were firstly obtained from this genus. The effects of different solvent soluble fractions of the ethanol extract and the pure compounds on heptocyte death induced by D-galactosamine (D-GalN)/tumor necrosis factor alpha (TNF-alpha) were studied, and the structure-activity relationships were also discussed.
从山银花（Lonicera bournei Hemsl.）花蕾的乙醇提取物中分离出13种奎尼酸衍生物，以及咖啡酸、咖啡酸甲酯、肌醇、双[5-甲酰基糠基]醚和6,7-二羟基香豆素，其中8种化合物首次从该属植物中获得。研究了乙醇提取物不同溶剂可溶部分及纯化合物对D-氨基半乳糖（D-GalN）/肿瘤坏死因子α（TNF-α）诱导的肝细胞死亡的影响，并探讨了构效关系。
