Guthrie E, Kapur N, Mackway-Jones K, Chew-Graham C, Moorey J, Mendel E, Marino-Francis F, Sanderson S, Turpin C, Boddy G, Tomenson B
School of Psychiatry and Behavioural Sciences, University of Manchester, Rawnsley Building, Manchester Royal Infirmary, Manchester M13 9WL.
BMJ. 2001 Jul 21;323(7305):135-8. doi: 10.1136/bmj.323.7305.135.
To determine the effects of a brief psychological intervention (brief psychodynamic interpersonal therapy) for patients after deliberate self poisoning compared with usual treatment. To compare the impact of the active intervention and usual treatment on patients' satisfaction with care.
Randomised controlled trial.
119 adults who had deliberately poisoned themselves and presented to the emergency department of a teaching hospital.
Community based study.
Four sessions of therapy delivered in the patient's home. Control patients received "treatment as usual," which in most cases consisted of referral back to their general practitioner.
Severity of suicidal ideation six months after treatment as assessed by the Beck scale for suicidal ideation. Secondary outcome measures at six month follow up included depressive symptoms as measured by the Beck depression inventory, patient satisfaction with treatment, and self reported subsequent attempts at self harm.
Participants randomised to the intervention had a significantly greater reduction in suicidal ideation at six month follow up compared with those in the control group (reduction in the mean (SD) Beck scale 8.0 v 1.5). They were more satisfied with their treatment and were less likely to report repeated attempts to harm themselves at follow up (proportion repeating 9% v 28% in control group; difference 19%, 95% confidence interval 9% to 30 %, P=0.009).
Brief psychodynamic interpersonal therapy may be a valuable treatment after people have deliberately tried to poison themselves.
确定与常规治疗相比,针对蓄意自我中毒患者的简短心理干预(简短心理动力人际治疗)的效果。比较积极干预和常规治疗对患者护理满意度的影响。
随机对照试验。
119名蓄意自我中毒并前往一家教学医院急诊科就诊的成年人。
基于社区的研究。
在患者家中进行四次治疗。对照患者接受“常规治疗”,在大多数情况下包括转诊回他们的全科医生处。
治疗六个月后用贝克自杀意念量表评估自杀意念的严重程度。六个月随访时的次要观察指标包括用贝克抑郁量表测量的抑郁症状、患者对治疗的满意度以及自我报告的后续自我伤害企图。
随机分配到干预组的参与者在六个月随访时自杀意念的减少幅度显著大于对照组(贝克量表平均(标准差)减少幅度8.0对1.5)。他们对治疗更满意,随访时报告再次企图伤害自己的可能性更小(重复比例9%对对照组的28%;差异19%,95%置信区间9%至30%,P = 0.009)。
简短心理动力人际治疗对于蓄意自我中毒者而言可能是一种有价值的治疗方法。