中国人群健康成年人心血管危险因素的患病率及聚集情况：台湾 MJ 健康筛查中心研究

Prevalence and clustering of cardiovascular risk factors among healthy adults in a Chinese population: the MJ Health Screening Center Study in Taiwan.

作者信息

Wu D M, Pai L, Chu N F, Sung P K, Lee M S, Tsai J T, Hsu L L, Lee M C, Sun C A

机构信息

School of Public Health, National Defense Medical Center, Taipei, Taiwan, Republic of China.

出版信息

Int J Obes Relat Metab Disord. 2001 Aug;25(8):1189-95. doi: 10.1038/sj.ijo.0801679.

DOI:10.1038/sj.ijo.0801679

PMID:11477504

Abstract

OBJECTIVE

To gain insight into the prevalence and clustering of multiple cardiovascular risk factors in a healthy Chinese adult population in Taiwan.

DESIGN

A cross-sectional study was carried out in 1996.

SUBJECTS

A total of 46,603 subjects (23,485 men and 23,118 women) who were aged 20--59 y and attended a private health screening center for health examination of their own volition.

MEASUREMENTS

Multiple cardiovascular risk factors including cigarette smoking, overweight (23 kg/m(2)< or =body mass index (BMI)<25 kg/m(2)) and obesity (BMI> or =25 kg/m(2)), lipid disorder (a ratio of total cholesterol level to the level of high density lipoprotein cholesterol>5 or use of lipid-lowering drugs), hypertension (systolic blood pressure> or =140 mmHg or diastolic blood pressure> or =90 mmHg or use of anti-hypertensive medications), and diabetes mellitus (fasting serum plasma glucose level> or =126 mg/dl or use of anti-diabetic medications) were determined.

RESULTS

In comparison to women, men had a higher prevalence of current smoking (42.1 vs 5.6%), overweight (25.1 vs 17.1%) and obesity (33.1 vs 21.5%), lipid disorder (45.1 vs 19.6%), hypertension (17.4 vs 13.2%), as well as diabetes mellitus (4.1 vs 3.4%). The prevalence of men or women having two or more of the cardiovascular risk factors of interest was 54.3 and 21.7%, respectively. With advancing age, the prevalence of risk factors became greater for both genders. More importantly, the clustering of risk factors increased monotonically with increasing BMI levels for men and women.

CONCLUSIONS

The prevalence and clustering of cardiovascular risk factors are commonplace in this healthy Chinese adult population. Considering the significant association between clustering of risk factors under study and BMI levels, this study gives an indication that population-based multifactorial interventions may work out favorably for specific groups.

摘要

目的

深入了解台湾健康成年人群中多种心血管危险因素的患病率及聚集情况。

设计

1996年开展了一项横断面研究。

研究对象

共有46603名年龄在20至59岁之间、自愿前往一家私立健康筛查中心进行健康检查的受试者（男性23485名，女性23118名）。

测量指标

测定了多种心血管危险因素，包括吸烟、超重（体重指数[BMI]为23kg/m²≤BMI＜25kg/m²）和肥胖（BMI≥25kg/m²）、血脂异常（总胆固醇水平与高密度脂蛋白胆固醇水平之比＞5或使用降脂药物）、高血压（收缩压≥140mmHg或舒张压≥90mmHg或使用抗高血压药物）以及糖尿病（空腹血清葡萄糖水平≥126mg/dl或使用抗糖尿病药物）。

结果

与女性相比，男性当前吸烟、超重、肥胖、血脂异常、高血压以及糖尿病的患病率更高（分别为42.1%对5.6%、25.1%对17.1%、33.1%对21.5%、45.1%对19.6%、17.4%对13.2%、4.1%对3.4%）。男性和女性中具有两种或更多所关注心血管危险因素的患病率分别为54.3%和21.7%。随着年龄增长，男女两性危险因素的患病率均升高。更重要的是，男性和女性的危险因素聚集情况均随BMI水平升高而单调增加。