Ohaeri O C
Department of Biochemistry, Faculty of Medical Sciences, University of Jos, Nigeria.
Biosci Rep. 2001 Feb;21(1):19-24. doi: 10.1023/a:1010425932561.
Levels of red cell, serum acid, and alkaline phosphatases, serum amylase, alanine and aspartate transferase and bilirubin were examined in streptozotocin-induced diabetic rats treated with garlic oil and compared with the corresponding levels in diabetic control rats, normal rats and normal rats on garlic oil. Values of tissue amylase and total protein were also assessed from the pancreas, liver, and kidney. Treatment of diabetic rats with garlic oil significantly decreased the red cell phosphatase (p < 0.01), serum acid and alkaline phosphatase (p<0.001) when compared to diabetic control rats. Serum alanine and asparate transferases were significantly (p<0.001) decreased as well as serum amylase (p<0.002) in garlic oil treated diabetic rats as compared with diabetic control rats. When treated with garlic oil, however, diabetic and normal rats showed significant increase (p <0.05) in the amylase levels of the pancrease, liver, and kidney.
对用大蒜油治疗的链脲佐菌素诱导的糖尿病大鼠，检测其红细胞、血清酸性和碱性磷酸酶、血清淀粉酶、丙氨酸和天冬氨酸转氨酶以及胆红素水平，并与糖尿病对照大鼠、正常大鼠以及服用大蒜油的正常大鼠的相应水平进行比较。还评估了胰腺、肝脏和肾脏的组织淀粉酶和总蛋白值。与糖尿病对照大鼠相比，用大蒜油治疗糖尿病大鼠可显著降低红细胞磷酸酶（p<0.01）、血清酸性和碱性磷酸酶（p<0.001）。与糖尿病对照大鼠相比，用大蒜油治疗的糖尿病大鼠血清丙氨酸和天冬氨酸转氨酶以及血清淀粉酶也显著降低（p<0.001）（p<0.002）。然而，在用大蒜油治疗时，糖尿病大鼠和正常大鼠胰腺、肝脏和肾脏的淀粉酶水平显著升高（p<0.05）。
