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局部应用物质的卵泡渗透研究。

Investigation of follicular penetration of topically applied substances.

作者信息

Lademann J, Otberg N, Richter H, Weigmann H J, Lindemann U, Schaefer H, Sterry W

机构信息

Center of Experimental and Applied Cutaneous Physiology, Dermatological Clinic, Medical Faculty Charité, Humboldt University, Berlin, Germany.

出版信息

Skin Pharmacol Appl Skin Physiol. 2001;14 Suppl 1:17-22. doi: 10.1159/000056385.

DOI:10.1159/000056385
PMID:11509902
Abstract

The influence of specific follicle properties, sebum production and hair growth on the follicular penetration of topically applied substances was investigated. The behavior of follicles identified in selected skin areas of volunteers was analyzed by various tape stripping and staining methods in combination with laser scanning microscopy. Furthermore hair growth in the selected skin areas was determined. A correlation between sebum production, hair growth activity and follicular penetration was observed.

摘要

研究了特定毛囊特性、皮脂分泌和头发生长对局部应用物质毛囊渗透的影响。通过各种胶带剥离和染色方法结合激光扫描显微镜,分析了志愿者选定皮肤区域中毛囊的行为。此外,还测定了选定皮肤区域的头发生长情况。观察到皮脂分泌、头发生长活性与毛囊渗透之间存在相关性。

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Investigation of follicular penetration of topically applied substances.局部应用物质的卵泡渗透研究。
Skin Pharmacol Appl Skin Physiol. 2001;14 Suppl 1:17-22. doi: 10.1159/000056385.
2
[Follicular penetration. An important pathway for topically applied substances].[滤泡渗透。局部应用物质的一条重要途径]
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Semiquantitative determination of the penetration of a fluorescent hydrogel formulation into the hair follicle with and without follicular closure by microparticles by means of differential stripping.通过差异剥离法对有或无毛囊闭合情况下荧光水凝胶制剂通过微粒渗透到毛囊中的情况进行半定量测定。
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Differential stripping: determination of the amount of topically applied substances penetrated into the hair follicles.差异剥离法:测定局部应用物质渗透入毛囊的量。
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The role of hair follicles in the percutaneous absorption of caffeine.毛囊在咖啡因经皮吸收中的作用。
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