Kyriakopoulou I, Magiatis P, Skaltsounis A L, Aligiannis N, Harvala C
Laboratory of Pharmacognosy, University of Athens, Panepistimiopolis, Zografou, GR-15771 Athens, Greece.
J Nat Prod. 2001 Aug;64(8):1095-7. doi: 10.1021/np010128+.
A new phenylethanoid glycoside, samioside, was isolated from the aerial parts of Phlomis samia and identified as 1-O-3,4-(dihydroxyphenyl)ethyl beta-D-apiofuranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->3)-4-O-caffeoyl-beta-D-glucopyranoside (1). In addition, one known phenylethanoid glycoside and three known flavonoids were identified as acteoside (2), apigenin, chrysoeriol, and ermanin, respectively. The structure of 1 was elucidated on the basis of its spectroscopic data. Samioside (1) demonstrated scavenging properties toward the DPPH radical and antimicrobial activity against Gram-positive and -negative bacteria.
从绵毛水苏地上部分分离得到一种新的苯乙醇苷——水苏苷，其结构鉴定为1-O-3,4-(二羟基苯基)乙基-β-D-芹菜呋喃糖基-(1→4)-α-L-鼠李吡喃糖基-(1→3)-4-O-咖啡酰基-β-D-吡喃葡萄糖苷(1)。此外，还分别鉴定出一种已知的苯乙醇苷和三种已知的黄酮类化合物，即毛蕊花糖苷(2)、芹菜素、 Chrysoeriol和ermanin。根据其光谱数据阐明了化合物1的结构。水苏苷(1)对DPPH自由基具有清除活性，对革兰氏阳性菌和阴性菌具有抗菌活性。
