新生儿成熟度研究。VII. 胎儿血红蛋白。

Studies on maturity in newborn infants. VII. Foetal haemoglobin.

作者信息

Finnström O, Gothefors L, Zetterlund B

出版信息

Acta Paediatr Scand. 1975 May;64(3):404-8. doi: 10.1111/j.1651-2227.1975.tb03855.x.

DOI:10.1111/j.1651-2227.1975.tb03855.x

Abstract

Cord blood from 125 newborns of various gestational ages has been analysed for the ratio foetal haemoglobin to total haemoglobin, using an alkali denaturation method. The quotient, percentage of foetal haemoglobin divided by birth weight correlates well with gestational age. Thus the percentage of foetal haemoglobin in cord blood can be used as a method for estimating maturity in newborn infants. Foetal haemoglobin has been compared with other methods for maturity assessments and seems to give the same precision in estimating gestational age as the best of these, which is the scoring of external characteristics. However, the latter method is considerably less time-consuming and more suitable for routine use.

摘要

采用碱变性法对125例不同孕周新生儿的脐血进行了胎儿血红蛋白与总血红蛋白比例的分析。胎儿血红蛋白百分比除以出生体重所得的商与孕周密切相关。因此，脐血中胎儿血红蛋白的百分比可作为评估新生儿成熟度的一种方法。已将胎儿血红蛋白与其他评估成熟度的方法进行了比较，在估计孕周方面，它似乎与这些方法中最佳的方法（即外部特征评分）具有相同的精度。然而，后一种方法耗时少得多，更适合常规使用。