Wiles N J, Scott D G, Barrett E M, Merry P, Arie E, Gaffney K, Silman A J, Symmons D P
ARC Epidemiology Unit, University of Manchester Medical School, Oxford Road, Manchester M13 9PT, UK.
Ann Rheum Dis. 2001 Oct;60(10):956-61. doi: 10.1136/ard.60.10.956.
Treatment, and therefore outcome, of rheumatoid arthritis (RA) will improve in the next few years. However, improvement in outcome can only be judged against the probability of certain outcomes with current conventional treatment.
To document the five year outcome of RA in the late 1990s.
Norfolk Arthritis Register (NOAR).
Longitudinal observational cohort study.
318 patients with recent onset inflammatory polyarthritis recruited by NOAR in 1990-91 completed five years of follow up. Four groups were assessed: the whole cohort, all those referred to hospital, those who satisfied criteria for RA at baseline, and those referred to hospital who satisfied criteria for RA at baseline. Outcome was assessed with a visual analogue scale for pain, the Health Assessment Questionnaire (HAQ), and the Short Form-36 (SF-36).
Of the RA hospital attenders, 50% had a visual analogue scale pain score of 5 cm or less and an HAQ score of 1.125 or less. SF-36 scores were reduced in all domains. Results are presented as cumulative percentages.
These results can be used for comparison and to set targets for improvement.
类风湿关节炎（RA）的治疗及相应的治疗效果在未来几年将会得到改善。然而，治疗效果的改善只能与当前传统治疗下某些结果出现的可能性进行对比来评判。
记录20世纪90年代末类风湿关节炎的五年治疗结果。
诺福克关节炎登记处（NOAR）。
纵向观察队列研究。
1990年至1991年由NOAR招募的318例近期发病的炎性多关节炎患者完成了五年的随访。评估了四组：整个队列、所有转诊至医院的患者、基线时符合类风湿关节炎标准的患者以及转诊至医院且基线时符合类风湿关节炎标准的患者。采用视觉模拟疼痛量表、健康评估问卷（HAQ）和简明健康调查问卷（SF-36）评估治疗结果。
在类风湿关节炎住院患者中，50%的患者视觉模拟疼痛量表评分在5厘米或以下，HAQ评分在1.125或以下。SF-36评分在所有领域均降低。结果以累积百分比表示。
这些结果可用于比较并设定改善目标。
