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日本代表性人群中年龄相关性黄斑病变的患病率:久山研究

Prevalence of age related maculopathy in a representative Japanese population: the Hisayama study.

作者信息

Oshima Y, Ishibashi T, Murata T, Tahara Y, Kiyohara Y, Kubota T

机构信息

Department of Ophthalmology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

出版信息

Br J Ophthalmol. 2001 Oct;85(10):1153-7. doi: 10.1136/bjo.85.10.1153.

Abstract

AIM

To determine the prevalence of age related maculopathy (ARM) in a representative older Japanese population.

METHODS

1486 residents of Hisayama town, Fukuoka, Japan, aged 50 years or older were examined and the presence of ARM was determined by grading from fundus examination by indirect ophthalmoscope, slit lamp, and colour fundus photographs.

RESULTS

The prevalence rate of drusen, which occurred with comparable frequency in men and women, was 9.6%. The frequency of drusen increased with age (p <0.01). Hyperpigmentation and/or hypopigmentation of the retina was present in 3.2%, geographic atrophy in 0.2%, and neovascular age related macular degeneration in 0.67%. The frequency of neovascular age related macular degeneration was significantly higher in the men (1.2% v. 0.34%, p <0.01).

CONCLUSIONS

Early and late stage ARM is less common among Japanese people than among white people in Western countries, while late stage ARM is more common among Japanese than among black people.

摘要

目的

确定具有代表性的老年日本人群中年龄相关性黄斑病变(ARM)的患病率。

方法

对日本福冈县久山町1486名年龄在50岁及以上的居民进行检查,通过间接检眼镜、裂隙灯眼底检查及彩色眼底照片分级来确定是否存在ARM。

结果

玻璃膜疣的患病率为9.6%,在男性和女性中出现频率相当。玻璃膜疣的频率随年龄增加而升高(p<0.01)。视网膜色素沉着过度和/或色素沉着不足的发生率为3.2%,地图样萎缩为0.2%,新生血管性年龄相关性黄斑变性为0.67%。新生血管性年龄相关性黄斑变性在男性中的发生率显著高于女性(1.2%对0.34%,p<0.01)。

结论

在日本人群中,早期和晚期ARM比西方国家的白种人少见,而晚期ARM在日本人中比黑人中更常见。

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