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不同嗜睡测量指标(多次睡眠潜伏期试验、瞳孔描记法和斯坦福嗜睡量表)的昼夜变化及其相互关系。

Time-of-day variations in different measures of sleepiness (MSLT, pupillography, and SSS) and their interrelations.

作者信息

Danker-Hopfe H, Kraemer S, Dorn H, Schmidt A, Ehlert I, Herrmann W M

机构信息

Interdisciplinary Sleep Clinic, Department of Psychiatry, Benjamin Franklin University Hospital, Free University of Berlin, Germany.

出版信息

Psychophysiology. 2001 Sep;38(5):828-35.

PMID:11577906
Abstract

The aim of the present study is to analyze how well physiological measures of sleepiness derived from pupillography and the Multiple Sleep Latency Test correlate with a subjective measure, the Stanford Sleepiness Scale (SSS) score. The results are based on data from 12 healthy participants, who underwent these tests every 2 hr from 7:00 a.m. until 11:00 p.m. Sleep latencies were correlated with four different variables derived from pupillography and the SSS score. The results indicate that the physiologically based variables correspond very well. This is reflected by similar patterns of time-of-day variations, a good agreement at the group level, and correlations at the individual level, whereas the SSS shows a quite different pattern of variation. The two physiological measures of sleepiness seem to reflect the same aspect of the level of tonic central nervous activation, which is not correlated with the subjective feeling of sleepiness.

摘要

本研究的目的是分析从瞳孔描记法和多次睡眠潜伏期试验得出的困倦生理指标与主观指标——斯坦福嗜睡量表(SSS)评分之间的关联程度。研究结果基于12名健康参与者的数据,这些参与者从上午7点到晚上11点每隔2小时接受一次这些测试。睡眠潜伏期与从瞳孔描记法得出的四个不同变量以及SSS评分相关。结果表明,基于生理的变量之间的对应关系非常好。这体现在一天中不同时间的变化模式相似、组水平上的良好一致性以及个体水平上的相关性,而SSS则呈现出截然不同的变化模式。两种困倦生理指标似乎反映了紧张性中枢神经激活水平的同一方面,这与主观困倦感无关。

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