Peacock M E, Hokett S D, Hellstein J W, Herold R W, Matzenbacher S A, Scales D K, Cuenin M F
US Army Dental Activity, Fort Gordon, GA 30905, USA.
J Periodontol. 2001 Sep;72(9):1287-90. doi: 10.1902/jop.2000.72.9.1287.
Plasma cell granulomas (pseudotumors) are rare benign, tumor-like proliferations composed chiefly of plasma cells that manifest primarily in the lungs, but may occur in various anatomic locations. We report this case of a 54-year-old male who presented with an unusual maxillary anterior gingival overgrowth treated by excisional biopsy. Histological examination revealed a dense inflammatory cell infiltrate containing mainly plasma cells. Immunohistochemistry for kappa and lambda light chains showed a polyclonal staining pattern confirming a diagnosis of plasma cell granuloma. Intraoral plasma cell granuloma is exceedingly rare, although case reports documenting such lesions have been reported. This case highlights the need to biopsy unusual lesions to rule out potential neoplasms.
浆细胞性肉芽肿（假瘤）是一种罕见的良性、肿瘤样增生，主要由浆细胞组成，主要表现在肺部，但也可能发生在各种解剖部位。我们报告了一例54岁男性患者，其表现为上颌前部牙龈异常增生，通过切除活检进行治疗。组织学检查显示有密集的炎性细胞浸润，主要为浆细胞。κ和λ轻链的免疫组化显示多克隆染色模式，确诊为浆细胞性肉芽肿。口腔内浆细胞性肉芽肿极为罕见，尽管已有记录此类病变的病例报告。该病例强调了对异常病变进行活检以排除潜在肿瘤的必要性。
