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[菲利普·莫帕斯:乙肝疫苗发现者]

[Philippe Maupas : hepatitis B vaccine discoverer].

作者信息

Chiron J P, Coursaget P, Yvonnet B

机构信息

Laboratoire de microbiologie-immunologie, Faculte des sciences pharmaceutiques, Tours.

出版信息

Rev Hist Pharm (Paris). 1998;46(319):279-92.

Abstract

Philippe Maupas Day 8th February 1981, an official ceremony with all the Profession, the Tours Faculty of Pharmacy was called Philippe Maupas, Hepatitis B vaccine discoverer - Galien Prize 1981. This communication presents the man, the scientist and the teacher. Born on 30th June 1939 in Toulon (south of France), married and the father of two children, Ph. Maupas was a man of action and an humanist. Full of enthusiasm, always available, passionate about his work, he never hesitated to brave the odds if he felt it would be of use to the community. With a pluridisciplinary training - Veterinary Doctor (1965), Pharmacist (1970), Science Doctor (1970) and Physician Doctor (1976) - he was Professor of Microbiology and Dean of the Faculty of Pharmacy of Tours. His scientific career fully illustrates his thirst for knowledge and his unflagging struggle against infectious diseases. Ph. Maupas approached his research work in a relaxed, imaginative frame of mind. Always passionate about his work and fired by spirit of Louis Pasteur, he was moved by a preoccupation of efficacy and a will of prevention in Public Health. He carried out research into both animal and human infectious diseases as well as anthropozoonosis. Ph. Maupas's most remarkable discoveries concerned the hepatitis B virus: he produced the first vaccine against hepatitis B and applied it to the prevention in man of this disease (1976); he confirmed the aetiological link between the hepatitis B and primary liver cancer.

摘要

菲利普·莫帕斯日 1981年2月8日,图尔大学药学院举行了一场有全体药学界人士参加的官方仪式,该仪式被命名为菲利普·莫帕斯,乙型肝炎疫苗发现者——1981年盖伦奖。本文介绍了这位人物、科学家和教师。菲利普·莫帕斯1939年6月30日出生于法国南部的土伦,已婚,育有两个孩子,他是一个行动派和人道主义者。他充满热情,随时待命,对工作满怀激情,如果觉得对社会有益,他从不犹豫去勇敢面对困难。他接受过多学科培训——兽医(1965年)、药剂师(1970年)、理学博士(1970年)和医学博士(1976年)——他是图尔大学药学院微生物学教授兼院长。他的科学事业充分体现了他对知识的渴望以及他与传染病不懈斗争的精神。菲利普·莫帕斯以轻松、富有想象力的心态开展他的研究工作。他始终对工作充满热情,受路易·巴斯德精神的激励,他被公共卫生领域对疗效的关注和预防的意愿所打动。他对动物和人类传染病以及人畜共患病都进行了研究。菲利普·莫帕斯最卓越的发现与乙型肝炎病毒有关:他研制出了第一种乙型肝炎疫苗并将其应用于人类预防这种疾病(1976年);他证实了乙型肝炎与原发性肝癌之间的病因学联系。

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