Meissner G, Schröder K H
Am Rev Respir Dis. 1975 Feb;111(2):196-200. doi: 10.1164/arrd.1975.111.2.196.
Strains of the species Mycobacterium simiae give a positive niacin test. On the basis of their cultural and biochemical characteristics and by seroagglutination they can be classified into 2 subspecies. (1) The strains of serotype M. simiae 1 hydrolyze urea regularly and nicotinamide and pyrazinamide irregularly. They are photochromogenic after prolonged exposure to light. (2) The strains of serotype M. simiae 2 hydrolyze urea only. Three of 4 strains are scotochromogenic; the fourth has a pale pink pigment. Two of these strains possess alpha- and beta-esterase activity. The other two are negative in this test. Strains of M. habana are culturally and biochemically identical with the serotype M. simiae 1 and show the same serologic specificity as M. simiae 1. M. habana sera, after having been absorbed by M. simiae 1, retain a small amount of agglutinins specific for M. habana. We believe that the M. habana strains belong to the species M. simiae and are closely related to the serotype M. simiae 1.
猿猴分枝杆菌菌株烟酸试验呈阳性。根据其培养和生化特性以及血清凝集反应，它们可分为2个亚种。（1）血清型1的猿猴分枝杆菌菌株能正常水解尿素，对烟酰胺和吡嗪酰胺的水解则不规则。长时间光照后它们具有光致变色性。（2）血清型2的猿猴分枝杆菌菌株仅能水解尿素。4株菌株中有3株为暗产色菌；第4株有淡粉色色素。这些菌株中有2株具有α-和β-酯酶活性。另外两株在此试验中呈阴性。哈瓦那分枝杆菌菌株在培养和生化特性上与血清型1的猿猴分枝杆菌相同，并且与血清型1的猿猴分枝杆菌具有相同的血清学特异性。哈瓦那分枝杆菌血清被血清型1的猿猴分枝杆菌吸收后，仍保留少量对哈瓦那分枝杆菌特异的凝集素。我们认为哈瓦那分枝杆菌菌株属于猿猴分枝杆菌种，并且与血清型1的猿猴分枝杆菌密切相关。
