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医院获得性流感感染作为婴儿并发发热的一个原因。

Nosocomial influenza infection as a cause of intercurrent fevers in infants.

作者信息

Hall C B, Douglas R G

出版信息

Pediatrics. 1975 May;55(5):673-7.

PMID:1168894
Abstract

All patients on an infants' ward manifesting intercurrent fevers were studied for viral and bacterial etiology during a community outbreak of influenza A. During a one-month period, of 29 infants admitted to the ward, 17 were hospitalized for seven or more days. Intercurrent fever complicated the course of 13 (76%) of these 17 infants. Nosocomially acquired influenza A infection was found in 13 infants. Two of these also contracted a dual infection with influenza B. The fever lasted an average of 2.7 days with a peak of 38.2 to 39.8 C. Initial white blood cell counts tended to by high and shifted to the left. These infants appeared to be at high risk for developing lower respiratory tract disease. Seven of the 12 had infiltrates on chest X-ray, and five subsequently developed a secondary bacterial pneumonia. These infants tended to be young, five were under 6 months, and all but one had underlying cardiorespiratory disease. They also appeared to have prolonge shedding of influenza virus from their nasal secretions. Six of seven shed the virus for 7 or 21 days.

摘要

在甲型流感社区暴发期间,对婴儿病房所有出现并发发热的患者进行了病毒和细菌病因学研究。在为期一个月的时间里,该病房收治的29名婴儿中,有17名住院7天或更长时间。并发发热使这17名婴儿中的13名(76%)病程复杂化。在13名婴儿中发现了医院获得性甲型流感感染。其中2名还感染了乙型流感双重感染。发热平均持续2.7天,峰值为38.2至39.8摄氏度。初始白细胞计数往往较高并左移。这些婴儿似乎有发生下呼吸道疾病的高风险。12名婴儿中有7名胸部X光有浸润,5名随后发生继发性细菌性肺炎。这些婴儿往往年龄较小,5名在6个月以下,除1名外均有潜在的心肺疾病。他们的鼻腔分泌物中似乎也有甲型流感病毒的长时间排出。7名婴儿中有6名排出病毒的时间为7至21天。

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