Fomon S J, Filmer L J, Thomas L N, Anderson T A, Nelson S E
Acta Paediatr Scand. 1975 Mar;64(2):172-81. doi: 10.1111/j.1651-2227.1975.tb03818.x.
Fifteen fullterm female infants were enrolled in each of two feeding groups and all but one completed the proposed period of observation to age 112 days. Formulas prepared from the same ingredients (fat-free milk solids, a mixture of corn and coconut oils, lactose, vitamins and minerals) were fed ad libitum to both groups. Formula concentration was 54 kcal/100 ml for one group and 100 kcal/100 ml for the other. A limited selection of commercially prepared strained foods was permitted after 28 days of age. Weighed intakes of food were recorded for each day of study. During the internal 8 through 41 days of age, the infants fed the 54 kcal/100 ml formula consumed a considerably greater quantity of food but fewer calories than did those fed the 100 kcal/100 ml formula. Those fed the 54 kcal/100 ml formula also gained less weight. These differences between feeding groups were statistically significant. After 41 days of age, mean caloric intakes (kcal/kg/day) and rates of gain in weight were similar for the two feeding groups. The data provide a basis of speculation on the possible difference in allocation of calories to growth and non-growth in the two groups.
两个喂养组各纳入15名足月儿，除1名婴儿外，所有婴儿均完成了至112日龄的观察期。两组婴儿均随意喂食由相同成分（脱脂乳固体、玉米和椰子油混合物、乳糖、维生素和矿物质）配制的配方奶。一组配方奶浓度为54千卡/100毫升，另一组为100千卡/100毫升。28日龄后允许有限选择市售的罐装食品。记录研究期间每天的食物摄入量。在8至41日龄期间，喂食54千卡/100毫升配方奶的婴儿摄入的食物量比喂食100千卡/100毫升配方奶的婴儿多得多，但摄入的热量却少。喂食54千卡/100毫升配方奶的婴儿体重增加也较少。两组之间的这些差异具有统计学意义。41日龄后，两组的平均热量摄入量（千卡/千克/天）和体重增加率相似。这些数据为推测两组热量分配到生长和非生长方面的可能差异提供了依据。
