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A method to measure the amount of drug penetrated across the nail plate.

作者信息

Kim J H, Lee C H, Choi H K

机构信息

College of Pharmacy, Chosun University, Kwangju, Korea.

出版信息

Pharm Res. 2001 Oct;18(10):1468-71. doi: 10.1023/a:1012265125158.

DOI:10.1023/a:1012265125158
PMID:11697474
Abstract
摘要

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本文引用的文献

1
Permeability characteristics of the human nail plate.人指甲板的渗透性特征。
Int J Cosmet Sci. 1983 Dec;5(6):231-46. doi: 10.1111/j.1467-2494.1983.tb00348.x.
2
In-vitro permeability of the human nail and of a keratin membrane from bovine hooves: influence of the partition coefficient octanol/water and the water solubility of drugs on their permeability and maximum flux.人指甲及牛蹄角质膜的体外渗透性：正辛醇/水分配系数和药物水溶性对其渗透性及最大通量的影响。
J Pharm Pharmacol. 1997 Jan;49(1):30-4. doi: 10.1111/j.2042-7158.1997.tb06747.x.
3
Physicochemical characterization of the human nail: permeation pattern for water and the homologous alcohols and differences with respect to the stratum corneum.
Iontophoretic terbinafine HCL 1.0% delivery across porcine and human nails.
电渗涂敷盐酸特比萘芬 1.0%透过猪和人指甲的递送。
Mycopathologia. 2010 May;169(5):343-9. doi: 10.1007/s11046-009-9265-x. Epub 2009 Dec 13.
4
Ultraviolet C inactivation of dermatophytes: implications for treatment of onychomycosis.皮肤癣菌的紫外线C灭活：对甲癣治疗的意义。
Br J Dermatol. 2008 Jun;158(6):1239-46. doi: 10.1111/j.1365-2133.2008.08549.x. Epub 2008 Apr 10.
5
Nail swelling as a pre-formulation screen for the selection and optimisation of ungual penetration enhancers.指甲肿胀作为一种制剂前筛选方法，用于选择和优化指甲渗透促进剂。
Pharm Res. 2007 Dec;24(12):2207-12. doi: 10.1007/s11095-007-9368-3. Epub 2007 Jul 31.
人类指甲的物理化学特性：水及同系醇类的渗透模式以及与角质层的差异
J Pharm Pharmacol. 1983 Jan;35(1):28-33. doi: 10.1111/j.2042-7158.1983.tb04258.x.
4
Quantification of ciclopirox by high-performance liquid chromatography after pre-column derivatization. An example of efficient clean-up using silica-bonded cyano phases.柱前衍生化后用高效液相色谱法定量测定环吡酮。使用硅胶键合氰基固定相进行有效净化的一个实例。
J Chromatogr. 1985 May 3;339(2):451-6. doi: 10.1016/s0378-4347(00)84680-0.
5
Physicochemical characterization of the human nail: solvent effects on the permeation of homologous alcohols.人类指甲的物理化学特性：溶剂对同系醇渗透的影响。
J Pharm Pharmacol. 1985 Nov;37(11):771-5. doi: 10.1111/j.2042-7158.1985.tb04966.x.
6
Ciclopirox nail lacquer 8%: in vivo penetration into and through nails and in vitro effect on pig skin.8%环吡酮甲涂剂：对指甲的体内渗透及穿透情况以及对猪皮肤的体外作用
Skin Pharmacol. 1991;4(2):89-94. doi: 10.1159/000210929.
7
Loceryl nail lacquer--realization of a new galenical approach to onychomycosis therapy.罗每乐甲涂剂——一种治疗甲真菌病新药剂学方法的实现。
Clin Exp Dermatol. 1992 Sep;17 Suppl 1:26-8. doi: 10.1111/j.1365-2230.1992.tb00273.x.
8
Ultrastructural changes in onychomycosis during the treatment with bifonazole/urea ointment.联苯苄唑/尿素软膏治疗甲癣过程中的超微结构变化
Dermatology. 1992;185(1):32-6. doi: 10.1159/000247399.