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The synthesis of oligoribonucleotides. Part XI. Preparation of ribonucleoside 2'-acetal 3'-esters by selective deacylation.

作者信息

Reese C B, Stewart J C, van Boom J H, de Leeuw H P, Nagel J, de Rooy J F

出版信息

J Chem Soc Perkin 1. 1975(10):934-42. doi: 10.1039/p19750000934.

DOI:10.1039/p19750000934
PMID:1170189
Abstract
摘要

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1
The synthesis of oligoribonucleotides. Part XI. Preparation of ribonucleoside 2'-acetal 3'-esters by selective deacylation.寡核糖核苷酸的合成。第十一章。通过选择性脱酰作用制备核糖核苷2'-缩醛3'-酯。
J Chem Soc Perkin 1. 1975(10):934-42. doi: 10.1039/p19750000934.
2
The synthesis of oligoribonucleotides. X. Preparation of 2',3'-cyclic phosphates of ribonucleosides and diribonucleoside phosphates via phosphotriester intermediates.寡核糖核苷酸的合成。X. 通过磷酸三酯中间体制备核糖核苷2',3'-环磷酸酯和二核糖核苷磷酸酯。
J Chem Soc Perkin 1. 1973;21:2513-7. doi: 10.1039/p19730002513.
3
New light labile linker for solid phase synthesis of 2'-O-acetalester oligonucleotides and applications to siRNA prodrug development.新型光不稳定连接子用于 2'-O-乙酰基寡核苷酸的固相合成及其在 siRNA 前药开发中的应用。
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4
From ribonucleoside 5'-aldehydes to ribonucleoside 5'-C-phosphonates as building blocks for oligonucleotide synthesis.
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5
Ribonucleoside and ribonucleotide derivatives in polynucleotide synthesis.多核苷酸合成中的核糖核苷和核糖核苷酸衍生物。
Nucleic Acids Symp Ser. 1980(7):99-102.
6
Synthesis of oligoribonucleotides with ribonuclease T 1 .
Biochim Biophys Acta. 1972 Oct 27;281(3):338-46. doi: 10.1016/0005-2787(72)90447-9.
7
Recent progress in oligonucleotide synthesis.寡核苷酸合成的最新进展。
Acta Biochim Pol. 1996;43(1):37-44.
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Modification of end phosphate gruops in mono- and oligonucleotides.单核苷酸和寡核苷酸末端磷酸基团的修饰。
Nucleic Acids Res. 1976 Apr;3(4):903-16. doi: 10.1093/nar/3.4.903.
9
Understanding high diastereomeric discrimination in formation of oligoribonucleotide phosphorothioate linkages: the first study of pKa-dependent activation in solid-supported coupling of 2'-O-substituted ribonucleoside phosphoramidites.
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Synthesis and conformational properties of oligonucleotides incorporating 2'-O-phosphorylated ribonucleotides as structural motifs of pre-tRNA splicing intermediates.
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Synthesis of 2'-N-methylamino-2'-deoxyguanosine and 2'-N,N-dimethylamino-2'-deoxyguanosine and their incorporation into RNA by phosphoramidite chemistry.2'-N-甲基氨基-2'-脱氧鸟苷和 2'-N,N-二甲基氨基-2'-脱氧鸟苷的合成及其通过亚磷酰胺化学法掺入 RNA 中。
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Site-specific incorporation of N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (dG-AAF) into oligonucleotides using modified 'ultra-mild' DNA synthesis.
使用改良的“超温和”DNA合成方法将N-（脱氧鸟苷-8-基）-2-乙酰氨基芴（dG-AAF）位点特异性掺入寡核苷酸中。
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Chemical incorporation of 1-methyladenosine into oligonucleotides.1-甲基腺苷化学掺入寡核苷酸。
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Preparation of oligodeoxyribonucleoside phosphorodithioates by a triester method.用三酯法制备寡脱氧核糖核苷磷酰二硫酯
Nucleic Acids Res. 1994 May 25;22(10):1797-804. doi: 10.1093/nar/22.10.1797.
6
Solid-phase synthesis of oligoribonucleotides using 9-fluorenylmethoxycarbonyl (Fmoc) for 5'-hydroxyl protection.使用9-芴甲氧羰基（Fmoc）对5'-羟基进行保护的寡核糖核苷酸的固相合成。
Nucleic Acids Res. 1989 Apr 11;17(7):2379-90. doi: 10.1093/nar/17.7.2379.
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Synthesis and applications of oligoribonucleotides with selected 2'-O-methylation using the 2'-O-[1-(2-fluorophenyl)-4-methoxypiperidin-4-yl] protecting group.使用2'-O-[1-(2-氟苯基)-4-甲氧基哌啶-4-基]保护基团合成及应用具有特定2'-O-甲基化的寡核糖核苷酸
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8
New synthetic routes to synthons suitable for 2'-O-allyloligoribonucleotide assembly.适用于2'-O-烯丙基寡核糖核苷酸组装的合成子的新合成路线。
Nucleic Acids Res. 1991 Feb 25;19(4):733-8. doi: 10.1093/nar/19.4.733.
9
Synthesis of 3'-phosphates of diribonucleoside monophosphates via phosphotriester intermediates.通过磷酸三酯中间体合成二磷酸核苷单磷酸酯的3'-磷酸酯。
Nucleic Acids Res. 1976 Oct;3(10):2731-47. doi: 10.1093/nar/3.10.2731.
10
Synthesis of oligonucleotides with sequences identical with or analogous to the 3'-end of 16S ribosomal RNA of Escherichia coli: preparation of A-C-C-U-C-C via the modified phosphotriester method.合成与大肠杆菌16S核糖体RNA 3'-末端序列相同或相似的寡核苷酸：通过改良的磷酸三酯法制备A-C-C-U-C-C。
Nucleic Acids Res. 1977 Apr;4(4):1047-63. doi: 10.1093/nar/4.4.1047.