Luna L D, Higginbotham M L, Henry C J, Turnquist S E, Moore A S, Graham J C
Department of Veterinary Medicine and Surgery, University of Missouri-Columbia, Columbia, USA.
J Feline Med Surg. 2000 Dec;2(4):173-81. doi: 10.1053/jfms.2000.0092.
Non-ocular melanoma is considered to be a rare neoplasm in cats; however, more than 150 cases have been reported in the literature since 1961. The objective of this study was to characterise this tumour better by evaluating case outcome and survival data for cats with melanoma and to compare clinical and histopathological findings with those of previous reports. Twenty-three feline non-ocular melanomas were identified, the most common locations being the nose, digit and pinna. Cats with digital melanomas had survival rates similar to their canine counterparts. Histological assignation of benignity, malignancy or junctional activity was not found to be an accurate predictor of clinical behaviour. Melanoma should be considered as a differential diagnosis for cats presenting with pigmented or non-pigmented masses and histopathology is essential for definitive diagnosis, as other tumours may clinically appear quite similar. Regular follow-up examinations are recommended indefinitely for benign or malignant feline melanomas.
非眼黑色素瘤被认为是猫身上的一种罕见肿瘤；然而，自1961年以来，文献中已报道了150多例。本研究的目的是通过评估猫黑色素瘤病例的转归和生存数据，更好地描述这种肿瘤，并将临床和组织病理学发现与先前报告进行比较。确定了23例猫非眼黑色素瘤，最常见的部位是鼻子、趾部和耳廓。患有趾部黑色素瘤的猫的存活率与犬类相似。未发现良性、恶性或交界性活动的组织学分类是临床行为的准确预测指标。对于出现色素沉着或无色素肿块的猫，应将黑色素瘤视为鉴别诊断，组织病理学对于明确诊断至关重要，因为其他肿瘤在临床上可能看起来非常相似。建议对良性或恶性猫黑色素瘤进行无限期的定期随访检查。
