一只14岁猫咪胸腔积液中的恶性黑色素瘤。
Malignant melanoma in pleural effusion in a 14-year-old cat.
作者信息
Morges Michelle A, Zaks Karen
机构信息
Antech Diagnostics, 17672 Cowan # B, Irvine, CA 92614-6845, USA.
出版信息
J Feline Med Surg. 2011 Jul;13(7):532-5. doi: 10.1016/j.jfms.2011.05.011.
CASE DETAILS
A 14-year-old female cat presented with signs of respiratory distress. Pleural fluid was found on radiographic assessment. Cytologic evaluation of the fluid revealed malignant melanocytosis. The cat had a previous history of a recurrent malignant melanoma near the base of the right ear. Due to declining clinical condition, the cat was euthanized.
CLINICAL SIGNIFICANCE
Cutaneous malignant melanomas (or melanosarcomas) are uncommon neoplasms in cats, and knowledge is limited. As far as the authors are aware, there are no previous reports in the veterinary literature of malignant melanocytes being identified in pleural effusion in cats, as they have in dogs. This report suggests that, despite conflicting information in the literature regarding the clinical behavior of cutaneous melanomas in cats, these tumors are capable of recurrence and metastasis. Aggressive treatment may be necessary even, as in this case, if the tumor is well differentiated on histopathology.
病例详情
一只14岁雌性猫出现呼吸窘迫症状。经放射学评估发现胸腔积液。对积液进行细胞学评估显示为恶性黑素细胞增多症。这只猫既往有右耳根部复发性恶性黑色素瘤病史。由于临床状况恶化，该猫实施了安乐死。
临床意义
皮肤恶性黑色素瘤（或黑色素肉瘤）在猫中是罕见的肿瘤，相关知识有限。据作者所知，兽医文献中此前尚无猫胸腔积液中发现恶性黑素细胞的报道，而在犬中则有此类报道。本报告表明，尽管文献中关于猫皮肤黑色素瘤临床行为的信息相互矛盾，但这些肿瘤能够复发和转移。即便在组织病理学上肿瘤分化良好，如本病例，积极治疗可能也是必要的。
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