Cull A, Gould A, House A, Smith A, Strong V, Velikova G, Wright P, Selby P
Imperial Cancer Research Fund, Medical Oncology Unit, Western General Hospital, Edinburgh, UK.
Br J Cancer. 2001 Dec 14;85(12):1842-9. doi: 10.1054/bjoc.2001.2182.
The aim of the study was to confirm the validity of using touchscreen computers for screening for clinically significant levels of distress among cancer patients in routine oncology practice. The Hospital Anxiety and Depression Scale (HADS), EORTC Quality of Life questionnaire (QLQ-C30), Mental Health Inventory-MHI5 and a Concerns Checklist were administered via touchscreen computer to 172 chemotherapy out-patients, twice, 2-4 weeks apart. A standard psychiatric interview (Present State Examination - PSE) was conducted within a week of the second assessment. On interview, 23% of patients were identified as 'cases'. Using the available data (questionnaires, sociodemographic details, self-reported past psychiatric history), the best screening strategy combined scores from MHI-5 and HADS from a single time-point with the following rules: if MHI-5 < 11 = non-case; if MHI-5 > or = 11 then use HADS; then, if HADS > or = 9 = 'case' (sensitivity 85%; specificity 71%; misclassification rate 26%; positive predictive value 47%). The computerized screening system enabled data to be collected, scored, collated and reported in real time to identify patients who warrant further clinical assessment. It offers the potential for improving 'case' detection in routine oncology practice while reducing the burden of questions put to 'non-cases'. Further work is needed to develop optimal choice of screening questions for this purpose.
本研究的目的是在肿瘤学常规实践中,确认使用触摸屏电脑对癌症患者进行具有临床意义的痛苦水平筛查的有效性。通过触摸屏电脑,对172名化疗门诊患者进行了两次医院焦虑抑郁量表(HADS)、欧洲癌症研究与治疗组织生活质量问卷(QLQ-C30)、心理健康量表MHI-5以及一份关注事项清单的调查,两次调查间隔2至4周。在第二次评估后的一周内进行了标准的精神科访谈(现况检查 - PSE)。访谈中,23%的患者被确定为“病例”。利用现有数据(问卷、社会人口学细节、自我报告的既往精神病史),最佳筛查策略将来自单一时间点的MHI-5和HADS得分相结合,并遵循以下规则:如果MHI-5<11 =非病例;如果MHI-5≥11,则使用HADS;然后,如果HADS≥9 =“病例”(敏感性85%;特异性71%;错误分类率26%;阳性预测值47%)。该计算机化筛查系统能够实时收集、评分、整理和报告数据,以识别需要进一步临床评估的患者。它为在肿瘤学常规实践中改善“病例”检测提供了潜力,同时减轻了对“非病例”提出的问题负担。为此,需要进一步开展工作以确定筛查问题的最佳选择。