Tsen L C, Thomas J, Segal S, Datta S, Bader A M
Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, and Department of Anaesthesia, Harvard Medical School, Boston, MA 02115, USA.
J Clin Anesth. 2001 Dec;13(8):571-5. doi: 10.1016/s0952-8180(01)00332-4.
To evaluate whether transcutaneous electrical nerve stimulation (TENS) can increase the quality and duration of an initiation dose of bupivacaine used for the establishment of epidural labor analgesia.
Randomized, double-blind study.
Tertiary-care academic medical center.
40 ASA physical status I and II parturients in early, active spontaneous labor with a singleton, vertex term fetus, and requesting analgesia.
A standardized epidural technique with either an active or inactive TENS unit was performed. Before epidural placement, TENS intensity thresholds were determined with electrodes placed over the paraspinus muscles at T(10)-L(1), and S(2)-S(4); TENS settings for mode, cycle, and pulse width were standardized.
Data were collected at timed intervals on pain as measured by visual analog scale (VAS), sensory level (pinprick), motor blockade (Bromage score), cervical dilation, and duration of analgesia.
The duration of analgesia produced by the initial dose of epidural bupivacaine did not differ between groups (TENS turned off 82.3 +/- 26 [mean +/- SD] vs. TENS activated 80.7 +/- 40 min, p = 0.88). Kaplan-Meier survival analysis and Mantel-Cox log rank analysis showed no difference between the two treatments (p = 0.75). No difference in the quality of analgesia was observed between the two groups.
In healthy laboring parturients, the application of a TENS unit did not alter the quality or duration of an initiation dose of bupivacaine utilized for the establishment of epidural labor analgesia.
评估经皮电刺激神经疗法(TENS)能否提高用于建立硬膜外分娩镇痛的初始剂量布比卡因的质量和持续时间。
随机双盲研究。
三级医疗学术医学中心。
40例美国麻醉医师协会(ASA)身体状况为I级和II级的产妇,处于早期活跃自发分娩阶段,单胎头位足月胎儿,且要求镇痛。
采用标准化硬膜外技术,使用有源或无源TENS装置。在放置硬膜外导管前,将电极置于胸10至腰1以及骶2至骶4的椎旁肌上,确定TENS强度阈值;TENS的模式、周期和脉宽设置标准化。
在规定时间间隔收集数据,包括视觉模拟量表(VAS)测量的疼痛、感觉平面(针刺)、运动阻滞(Bromage评分)、宫颈扩张程度以及镇痛持续时间。
两组之间硬膜外布比卡因初始剂量产生的镇痛持续时间无差异(TENS关闭组为82.3±26[平均值±标准差]分钟,TENS开启组为80.7±40分钟,p = 0.88)。Kaplan-Meier生存分析和Mantel-Cox对数秩分析显示两种治疗方法无差异(p = 0.75)。两组之间镇痛质量无差异。
在健康的分娩产妇中,应用TENS装置并未改变用于建立硬膜外分娩镇痛的初始剂量布比卡因的质量或持续时间。