[腹内侧下丘脑的神经化学特征及抗焦虑药物在各种焦虑模型中的抗厌恶作用]
[Neurochemical characteristics of the ventromedial hypothalamus and anti-aversive effects of anxiolytic agents in various anxiety models].
作者信息
Talalaenko A N, Pankrat'ev D V, Goncharenko N V
机构信息
Gorky Medical University, Donetsk, 83003, Ilyich Ave., 16, Ukraine.
出版信息
Ross Fiziol Zh Im I M Sechenova. 2001 Sep;87(9):1217-26.
PMID:11763535
Abstract
Neurochemical analysis using anxiosedative and anxioselective agents injected into the hypothalamus revealed that antiaversive action of camprione is only realised under conditions of domineering fear motivation whereas that of chlordiazepoxide, phenibut, indoter may also be realised under conditions of negative stressful zoo-social impacts mediated by serotonin.
摘要
使用注射到下丘脑的抗焦虑和抗焦虑选择性药物进行神经化学分析表明，坎普里奥内的抗厌恶作用仅在占主导地位的恐惧动机条件下实现，而氯氮卓、苯乙胺、吲哚的抗厌恶作用也可能在由血清素介导的负面应激性动物社会影响条件下实现。
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