Varoli L, Burnelli S, Garuti L, Vitali B
Dipartimento di Scienze Farmaceutiche, Università degli Studi di Bologna, Italy.
Farmaco. 2001 Nov;56(11):885-90. doi: 10.1016/s0014-827x(01)01154-5.
A series of 4-diazoimidazole-5-carboxamides bearing in position 2 lipophilic substituents was synthesized and their antimicrobial activity was evaluated in vitro against pathogenic Gram-positive, Gram-negative bacteria and fungi. Some compounds presented antifungal activity, particularly two derivatives (1g and 1h) showed good MIC values (10-50 microg/ml) against both moulds and yeasts.
