芳香肽核酸的杂交特性：一类新型的寡核苷酸类似物。
Hybridization properties of aromatic peptide nucleic acids: a novel class of oligonucleotide analogues.
作者信息
Fader Lee D, Tsantrizos Youla S
机构信息
Department of Chemistry, McGill University, Montreal, Quebec, Canada H3A 2K6.
出版信息
Org Lett. 2002 Jan 10;4(1):63-6. doi: 10.1021/ol010231q.
PMID:11772091
Abstract
[structure: see text] The synthesis of APNA-PNA chimeras containing all four DNA bases will be described. The hybridization properties of APNA-PNA chimeras with DNA and RNA are consistent with plausible intramolecular interactions that could preorganize the oligomers in a duplex or triplex structure with complementary DNA or RNA.
摘要
[结构：见正文] 将描述包含所有四种DNA碱基的APNA-PNA嵌合体的合成。APNA-PNA嵌合体与DNA和RNA的杂交特性与合理的分子内相互作用一致，这种相互作用可以使寡聚物以与互补DNA或RNA形成双链或三链结构的方式进行预组装。
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