Hveem K, Jones K L, Chatterton B E, Horowitz M
Department of Medicine, Royal Adelaide Hospital, South Australia.
Gut. 1996 Jun;38(6):816-21. doi: 10.1136/gut.38.6.816.
Ultrasound measurement of gastric emptying has potential advantages over scintigraphy, but there is little information about its accuracy.
The relation between ultrasonographic measurements of antral area and (a) scintigraphic measurements of gastric emptying and intragastric distribution of liquids (b) postprandial satiation, were evaluated.
Seven normal volunteers were studied.
Each subject drank 75 g dextrose dissolved in 350 ml of water (300 kcal) or beef soup (20 kcal), both labelled with technetium-99m sulphur colloid on separate days and had measurement of gastric emptying by scintigraphy and ultrasound.
Scintigraphic and ultrasound 50% emptying times (T50s) were comparable and longer (p < 0.001) for dextrose than soup mean (SEM) (dextrose 107 (16) min v 108 (18) min, soup 24 (4) min v 23 (5) min). There were close correlations between scintigraphic and ultrasound T50s (dextrose r = 0.94, p < 0.005, soup r = 0.97, p < 0.001) and between the time at which the distal stomach content decreased from its maximum value by 50% (measured scintigraphically) and the ultrasound T50 (dextrose r = 0.95, p < 0.005, soup r = 0.99, p < 0.0001). In contrast, there was no significant relation between the distal stomach content when expressed as a percentage of the maximum content in the total stomach and the ultrasound T50. After dextrose, fullness was related (r = 0.92, p < 0.01) to the postprandial increase in antral area measured by ultrasound.
Ultrasound measurements of gastric emptying are: (a) of comparable sensitivity to scintigraphy in quantifying emptying of both low and high nutrient liquids (b) correlate with postprandial satiation, suggesting that the latter may be mediated by antral distension.
超声测量胃排空较闪烁扫描法具有潜在优势，但关于其准确性的信息较少。
评估胃窦面积超声测量值与（a）胃排空及液体胃内分布的闪烁扫描测量值，（b）餐后饱腹感之间的关系。
研究了7名正常志愿者。
每位受试者在不同日期分别饮用溶解于350毫升水（300千卡）中的75克葡萄糖或牛肉汤（20千卡），两者均用锝-99m硫胶体标记，并通过闪烁扫描法和超声测量胃排空。
葡萄糖组和汤组的闪烁扫描及超声50%排空时间（T50）具有可比性，且葡萄糖组的T50更长（p < 0.001），平均（标准误）（葡萄糖组107（16）分钟对108（18）分钟，汤组24（4）分钟对23（5）分钟）。闪烁扫描和超声T50之间存在密切相关性（葡萄糖组r = 0.94，p < 0.005，汤组r = 0.97，p < 0.001），以及远端胃内容物从最大值下降50%的时间（闪烁扫描测量）与超声T50之间也存在密切相关性（葡萄糖组r = 0.95，p < 0.005，汤组r = 0.99，p < 0.0001）。相比之下，以远端胃内容物占总胃最大内容物的百分比表示时，与超声T50之间无显著关系。饮用葡萄糖后，饱腹感与超声测量的餐后胃窦面积增加相关（r = 0.92，p < 0.01）。
胃排空的超声测量结果为：（a）在量化低营养和高营养液体排空方面与闪烁扫描法具有相当的敏感性；（b）与餐后饱腹感相关，提示后者可能由胃窦扩张介导。
