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[冬季住院老年患者发热病因:病毒性呼吸道感染]

[Viral respiratory infections as cause of fever in hospitalized aged patients during a winter season].

作者信息

Sivier V, Odelin M F, Gonthier R, Pozzetto B

机构信息

Service de gérontologie clinique, hôpital de la Charité, CHU, 42055 Saint-Etienne, France.

出版信息

Rev Med Interne. 2001 Dec;22(12):1180-7. doi: 10.1016/s0248-8663(01)00489-1.

Abstract

PURPOSE

In the geriatric units of the University Hospital of Saint-Etienne, 129 cases of fever (38 degrees C or more) were recorded prospectively during the 1995-1996 winter period in a population of 503 hospitalised patients (25.6%), and were investigated for the detection of a viral aetiology.

METHODS

In febrile patients, a standard form was used to record clinical and biological parameters, including the results of investigations for respiratory viruses from a nasal swab and dual serum specimens.

RESULTS

A clinical or radiological respiratory infection was found in 69 cases (53.5% of all cases of fever), including 14 respiratory syncytial virus (RSV) infections. In comparison to nonviral respiratory infections, the RSV infections were characterised by the prevalence of anorexia (57% vs 20%, P < 0.05) and rhinorrhea (64% vs 5%, P < 0.01). No influenza infection was recorded despite the concomitant circulation of influenza virus in the community. A nosocomial outbreak of RSV infection (nine cases, attack rate of 18.7%) was identified in a long-stay care unit.

CONCLUSION

This study illustrates the high prevalence (10.9%) of RSV infections in elderly patients with fever during this season and the importance of hygienic measures to control the spread of nosocomial outbreaks.

摘要

目的

在圣艾蒂安大学医院的老年病房,于1995 - 1996年冬季对503名住院患者(占25.6%)进行前瞻性记录,共记录到129例发热(体温38摄氏度及以上)病例,并对其进行病毒病因检测。

方法

对于发热患者,使用标准表格记录临床和生物学参数,包括鼻拭子及双份血清标本中呼吸道病毒的检测结果。

结果

69例(占所有发热病例的53.5%)发现有临床或放射学诊断的呼吸道感染,其中包括14例呼吸道合胞病毒(RSV)感染。与非病毒引起的呼吸道感染相比,RSV感染的特征为厌食发生率高(57%对20%,P < 0.05)和流涕发生率高(64%对5%,P < 0.01)。尽管社区中有流感病毒传播,但未记录到流感感染病例。在一个长期护理单元发现了一次RSV感染的医院内暴发(9例,罹患率为18.7%)。

结论

本研究表明该季节老年发热患者中RSV感染的患病率较高(10.9%),以及采取卫生措施控制医院内暴发传播的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f21/7127035/eb00c2294cd3/fx1.jpg

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