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对于患有巴雷特食管的患者,首选Roux-en-Y长襻转流术。

Roux-en-Y long limb diversion as the first option for patients who have Barrett's esophagus.

作者信息

Csendes Attila, Braghetto Italo, Burdiles Patricio, Korn Owen

机构信息

Department of Surgery, Clinical Hospital University of Chile, Santiago, Chile.

出版信息

Chest Surg Clin N Am. 2002 Feb;12(1):157-84. doi: 10.1016/s1052-3359(03)00072-3.

Abstract

In summary, vagotomy plus antrectomy and the Roux-en-Y procedure is based on the following points: (a) patients who have BE show several foregut abnormalities, including incompetent lower esophageal sphincter, impairment in the esophageal clearance, severe gastroesophageal acid reflux, and frequent duodenoesophageal reflux; (b) late results of classic antireflux procedure in BE are poor with a high recurrence rate owing to a progressive loosening of the wrap; (c) the esophageal damage is produced by the injurious component of the refluxate; and (d) among patients who underwent classic antireflux surgery, a certain proportion developed dysplasia or even adenocarcinoma in the follow-up. The authors have observed that the simple correction of the valve is not enough in many cases, because it does not abolish the gastroesophageal reflux but only diminishes it. In patients who have BE and therefore have impaired esophageal clearance, few reflux episodes can maintain or even induce more damage. With the reduction diversion antireflux procedure, the quality of the corrected valve is secondary, and the main goal is to avoid the reflux of injurious components of the refluxate instead of the refluxate itself, which is almost always impossible. Late results support this hypothesis, and the authors propose this surgical procedure as an alternative treatment in patients who have complicated BE or in patients who have long-segment BE. Among patients who have gastroesophageal reflux and intestinal metaplasia of the cardia or with a noncomplicated short-segment BE, laparoscopic antireflux surgery is the authors' first choice, and only the late objective evaluation of surgical treatment demonstrates which surgical technique is the more adequate to a particular patient who has BE.

摘要

总之,迷走神经切断术加胃窦切除术及Roux-en-Y手术基于以下几点:(a)患有Barrett食管(BE)的患者存在多种前肠异常,包括食管下括约肌功能不全、食管清除功能受损、严重的胃食管酸反流以及频繁的十二指肠食管反流;(b)经典抗反流手术治疗BE的远期效果不佳,由于包绕处逐渐松弛,复发率较高;(c)反流物的有害成分会造成食管损伤;(d)在接受经典抗反流手术的患者中,一定比例的患者在随访中出现了发育异常甚至腺癌。作者观察到,在许多情况下单纯纠正瓣膜是不够的,因为这并不能消除胃食管反流,而只是减轻反流。对于患有BE且食管清除功能受损的患者,少量反流发作就能维持甚至引发更多损伤。对于减少分流抗反流手术,纠正后瓣膜的质量是次要的,主要目标是避免反流物有害成分的反流,而不是反流物本身,而这几乎总是不可能的。远期结果支持这一假设,作者提出该手术方法可作为患有复杂BE或长段BE患者的替代治疗方法。在患有胃食管反流且贲门肠化生或非复杂性短段BE的患者中,腹腔镜抗反流手术是作者的首选,只有手术治疗的远期客观评估才能表明哪种手术技术更适合特定的BE患者。

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