Nunn D B
Ann Surg. 1975 Dec;182(6):733-8. doi: 10.1097/00000658-197512000-00014.
This paper offers a computer-assisted analysis of the author's experience with 234 carotid endarterectomy procedures in 188 patients. The patients' ages, sex, smoking habits, symptoms, carotid bruits, arteriographic findings and associated diseases are summarized. There were 28 operations in asymptomatic patients, 170 operations in patients with transient ischemic attacks (TIA), 35-operations in patients with a completed stroke and one operation in a patient with a stroke in evolution. After surgery, transient neurologic deficits were noted in both the asymptomatic group (two instances) and the group with TIA (5 instances); permanent neurologic deficits followed 4 operations in the TIA group (2.4% incidence). Two operative deaths occurred in the TIA group (1.2% mortality), and 10 deaths occured after operation for a completed stroke (28.6% mortality). Nine of the deaths in the completed stroke group followed operations performed less than 2 weeks after a stroke. A 100% followup was obtained, and the average period of followup was 48 months. Of the patients surviving operation, all in the asymptomatic group were judged functionally normal, 94% of the TIA group were either functionally normal or improved, 76% with a completed stroke were improved, and the patient with a stroke in evolution was unchanged. There were 69 late deaths with heart disease accounting for 58% of the deaths and stroke another 17%.
本文对作者为188例患者实施的234例颈动脉内膜切除术的经验进行了计算机辅助分析。总结了患者的年龄、性别、吸烟习惯、症状、颈动脉杂音、血管造影结果及相关疾病。无症状患者接受了28例手术,短暂性脑缺血发作(TIA)患者接受了170例手术,完全性卒中患者接受了35例手术,进展性卒中患者接受了1例手术。术后,无症状组(2例)和TIA组(5例)均出现了短暂性神经功能缺损;TIA组4例手术(发生率2.4%)后出现永久性神经功能缺损。TIA组发生2例手术死亡(死亡率1.2%),完全性卒中手术后发生10例死亡(死亡率28.6%)。完全性卒中组9例死亡发生在卒中后不到2周进行的手术之后。随访率为100%,平均随访期为48个月。在存活的手术患者中,无症状组所有患者功能均正常,TIA组94%功能正常或有所改善,完全性卒中患者76%有所改善,进展性卒中患者病情无变化。有69例晚期死亡,其中心脏病占死亡人数的58%,卒中占17%。