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水稻基因组(粳稻亚种)的草图序列。

A draft sequence of the rice genome (Oryza sativa L. ssp. japonica).

作者信息

Goff Stephen A, Ricke Darrell, Lan Tien-Hung, Presting Gernot, Wang Ronglin, Dunn Molly, Glazebrook Jane, Sessions Allen, Oeller Paul, Varma Hemant, Hadley David, Hutchison Don, Martin Chris, Katagiri Fumiaki, Lange B Markus, Moughamer Todd, Xia Yu, Budworth Paul, Zhong Jingping, Miguel Trini, Paszkowski Uta, Zhang Shiping, Colbert Michelle, Sun Wei-lin, Chen Lili, Cooper Bret, Park Sylvia, Wood Todd Charles, Mao Long, Quail Peter, Wing Rod, Dean Ralph, Yu Yeisoo, Zharkikh Andrey, Shen Richard, Sahasrabudhe Sudhir, Thomas Alun, Cannings Rob, Gutin Alexander, Pruss Dmitry, Reid Julia, Tavtigian Sean, Mitchell Jeff, Eldredge Glenn, Scholl Terri, Miller Rose Mary, Bhatnagar Satish, Adey Nils, Rubano Todd, Tusneem Nadeem, Robinson Rosann, Feldhaus Jane, Macalma Teresita, Oliphant Arnold, Briggs Steven

机构信息

Torrey Mesa Research Institute, Syngenta, 3115 Merryfield Row, San Diego, CA 92121, USA.

出版信息

Science. 2002 Apr 5;296(5565):92-100. doi: 10.1126/science.1068275.

DOI:10.1126/science.1068275
PMID:11935018
Abstract

The genome of the japonica subspecies of rice, an important cereal and model monocot, was sequenced and assembled by whole-genome shotgun sequencing. The assembled sequence covers 93% of the 420-megabase genome. Gene predictions on the assembled sequence suggest that the genome contains 32,000 to 50,000 genes. Homologs of 98% of the known maize, wheat, and barley proteins are found in rice. Synteny and gene homology between rice and the other cereal genomes are extensive, whereas synteny with Arabidopsis is limited. Assignment of candidate rice orthologs to Arabidopsis genes is possible in many cases. The rice genome sequence provides a foundation for the improvement of cereals, our most important crops.

摘要

水稻粳稻亚种是一种重要的谷物和单子叶植物模型,其基因组通过全基因组鸟枪法测序进行了测序和组装。组装后的序列覆盖了4.2亿碱基对基因组的93%。对组装序列的基因预测表明,该基因组包含32000至50000个基因。在水稻中发现了98%已知玉米、小麦和大麦蛋白质的同源物。水稻与其他谷物基因组之间的共线性和基因同源性广泛,而与拟南芥的共线性有限。在许多情况下,可以将候选水稻直系同源基因定位到拟南芥基因上。水稻基因组序列为改良谷物(我们最重要的作物)奠定了基础。

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