Marie-Cardine Aude, Gourlain Karine, Mouterde Olivier, Castignolles Nathalie, Hellot Marie-France, Mallet Eric, Buffet-Janvresse Claudine
Department of Medical Pediatrics, Rouen University Hospital, 76031 Rouen Cedex, France.
Clin Infect Dis. 2002 May 1;34(9):1170-8. doi: 10.1086/339807. Epub 2002 Apr 1.
This study assessed the epidemiologic characteristics of acute viral gastroenteritis in hospitalized children. A stool sample obtained from each child was analyzed for the presence of astrovirus, calicivirus, rotavirus, adenovirus, enterovirus, and digestive bacteria. Of the 438 stool samples obtained, 138 tested positive for > or =1 pathogen during the winters of 1997-1998 and 1998-1999 (P<.001). Virologic tests revealed rotavirus in 17.3% of samples, calicivirus in 7.3%, astrovirus in 6.8%, adenovirus in 0.7%, and > or =1 virus in 5.4%. Median age was higher for patients with rotavirus gastroenteritis than it was for those with astrovirus or calicivirus gastroenteritis (P=.014). Mean duration of hospitalization was statistically significantly lower for children with rotavirus gastroenteritis (P=.022), despite the more-frequent dehydration observed among children with rotavirus versus those with astrovirus or calicivirus gastroenteritis (P=.007). In contrast, enteral rehydration was more rapidly achieved in patients with gastroenteritis due to rotavirus.
本研究评估了住院儿童急性病毒性肠胃炎的流行病学特征。对每个儿童采集的粪便样本进行分析，检测是否存在星状病毒、杯状病毒、轮状病毒、腺病毒、肠道病毒和消化道细菌。在1997 - 1998年和1998 - 1999年冬季采集的438份粪便样本中，138份检测出≥1种病原体呈阳性（P<0.001）。病毒学检测显示，17.3%的样本中存在轮状病毒，7.3%存在杯状病毒，6.8%存在星状病毒，0.7%存在腺病毒，5.4%存在≥1种病毒。轮状病毒肠胃炎患者的年龄中位数高于星状病毒或杯状病毒肠胃炎患者（P = 0.014）。轮状病毒肠胃炎患儿的平均住院时间在统计学上显著较短（P = 0.022），尽管与星状病毒或杯状病毒肠胃炎患儿相比，轮状病毒肠胃炎患儿出现脱水的情况更频繁（P = 0.007）。相比之下，轮状病毒引起的肠胃炎患者通过肠内补液能更快实现补液。
