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TSH and PRL response to thyrotrophin-releasing hormone in children with chronic renal failure undergoing haemodialysis.接受血液透析的慢性肾衰竭儿童对促甲状腺激素释放激素的促甲状腺激素和催乳素反应
Arch Dis Child. 1979 Dec;54(12):937-41. doi: 10.1136/adc.54.12.937.
2
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Alteration of pituitary-thyroid function in patients with chronic renal failure treated by haemodialysis or continuous ambulatory peritoneal dialysis.接受血液透析或持续性非卧床腹膜透析治疗的慢性肾衰竭患者垂体-甲状腺功能的改变
Ann Clin Biochem. 1985 Mar;22 ( Pt 2):156-60. doi: 10.1177/000456328502200209.
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Human prolactin and thyrotropin concentrations in the serums of normal and hypopituitary children before and after the administration of synthetic thyrotropin-releasing hormone.正常儿童和垂体功能减退儿童在注射合成促甲状腺激素释放激素前后血清中的人催乳素和促甲状腺激素浓度
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Basal and TRH-stimulated thyroid and pituitary hormones in various degrees of renal insufficiency.不同程度肾功能不全时的基础及促甲状腺激素释放激素刺激下的甲状腺和垂体激素
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Sustained rises in serum thyrotropin, thyroxine, and triiodothyronine during long term, continuous thyrotropin-releasing hormone treatment in patients with amyotrophic lateral sclerosis.在肌萎缩侧索硬化症患者长期持续促甲状腺激素释放激素治疗期间，血清促甲状腺激素、甲状腺素和三碘甲状腺原氨酸持续升高。
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Effect of dexamethasone on prolactin and TSH responses to TRH and metoclopramide in man.地塞米松对人体催乳素及促甲状腺激素对促甲状腺激素释放激素和胃复安反应的影响。
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10
The effects of intranasally sprayed synthetic TRH on TSH and on PRL secretion in children.经鼻喷雾合成促甲状腺激素释放激素对儿童促甲状腺激素及催乳素分泌的影响。
Eur J Pediatr. 1983 Mar;140(1):17-8. doi: 10.1007/BF00661897.

引用本文的文献

1
Importance of specific reference values for evaluation of the deteriorating thyroid function in patients with end-stage renal disease on hemodialysis.特定参考值对评估血液透析终末期肾病患者甲状腺功能恶化的重要性。
J Endocrinol Invest. 2015 Jan;38(1):47-56. doi: 10.1007/s40618-014-0121-6. Epub 2014 Jul 5.

本文引用的文献

1
The effect of acute starvation on the thyrotrophic hormone level in the blood of the rat and mouse.急性饥饿对大鼠和小鼠血液中促甲状腺激素水平的影响。
Endocrinology. 1951 Mar;48(3):341-3.
2
RADIOIMMUNOASSAY OF HUMAN PLASMA THYROTROPIN.人血浆促甲状腺激素的放射免疫测定
J Clin Invest. 1965 Aug;44(8):1277-86. doi: 10.1172/JCI105234.
3
Hypothyroidism in cystinosis. A clinical, endocrinologic and histologic study involving sixteen patients with cystinosis.胱氨酸病中的甲状腺功能减退症。一项涉及16例胱氨酸病患者的临床、内分泌学和组织学研究。
Am J Med. 1970 Jun;48(6):678-92. doi: 10.1016/s0002-9343(70)80002-x.
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Exophthalmus in chronic renal insufficiency.慢性肾功能不全中的突眼症
Scand J Urol Nephrol. 1971;5(2):146-53. doi: 10.3109/00365597109133593.
5
Influence of heparin on serum free thyroxine.肝素对血清游离甲状腺素的影响。
J Clin Endocrinol Metab. 1969 Aug;29(8):1015-22. doi: 10.1210/jcem-29-8-1015.
6
Thyroid function in chronic renal failure: effects of chronic hemodialysis.慢性肾衰竭中的甲状腺功能：慢性血液透析的影响
Trans Am Soc Artif Intern Organs. 1972;18(0):244-9. doi: 10.1097/00002480-197201000-00061.
7
Abnormalities of in vitro thyroid function tests in renal disease.
Q J Med. 1974 Apr;43(170):245-61.
8
Prolactin and thyrotropin in thyroid diseases: lack of evidence for a physiological role of thyrotropin-releasing hormone in the regulation of prolactin secretion.甲状腺疾病中的催乳素和促甲状腺激素：促甲状腺激素释放激素在催乳素分泌调节中缺乏生理作用的证据。
Horm Metab Res. 1974 May;6(3):190-5. doi: 10.1055/s-0028-1093871.
9
[Study of plasma transport and metabolism of thyroid hormones in diabetes mellitus and various metabolic diseases].
Ann Endocrinol (Paris). 1970 May-Jun;31(3):350-62.
10
Effects of chronic hemodialysis on thyroid function in chronic renal failure.慢性血液透析对慢性肾衰竭患者甲状腺功能的影响。
Can Med Assoc J. 1973 Aug 18;109(4):282-6.

接受血液透析的慢性肾衰竭儿童对促甲状腺激素释放激素的促甲状腺激素和催乳素反应

TSH and PRL response to thyrotrophin-releasing hormone in children with chronic renal failure undergoing haemodialysis.

作者信息

Ijaiya K

出版信息

Arch Dis Child. 1979 Dec;54(12):937-41. doi: 10.1136/adc.54.12.937.

DOI:10.1136/adc.54.12.937
PMID:119489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1545744/
Abstract

Eight children (aged between 8 1/2 and 15 1/2 years) with chronic renal failure receiving intermittent haemodialysis, and 2 children with renal transplants were studied. The response of TSH and prolactin (PRL), and basal T4 and T3 values was measured. Basal TSH was normal, and rose only slightly after TRH stimulation. Plasma T4 and T3 were below normal levels in 6 children. Mean basal PRL was raised and could not be stimulated by TRH. This study demonstrates the involvement of the hypothalamus and pituitary in chronic renal disease. The cause of the abnormal secretion of TSH and PRL in chronic renal failure is discussed in the light of clinical importance.

摘要

对8名接受间歇性血液透析的慢性肾衰竭儿童（年龄在8.5至15.5岁之间）以及2名肾移植儿童进行了研究。测量了促甲状腺激素（TSH）和催乳素（PRL）的反应以及基础甲状腺素（T4）和三碘甲状腺原氨酸（T3）值。基础TSH正常，促甲状腺激素释放激素（TRH）刺激后仅略有升高。6名儿童的血浆T4和T3低于正常水平。平均基础PRL升高，且TRH不能刺激其升高。本研究证明了下丘脑和垂体参与慢性肾病。根据临床重要性讨论了慢性肾衰竭中TSH和PRL分泌异常的原因。