• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

一例血培养阴性的心内膜炎患者心脏瓣膜上优雅颗粒链菌的分子诊断

Molecular diagnosis of Granulicatella elegans on the cardiac valve of a patient with culture-negative endocarditis.

作者信息

Casalta J P, Habib G, La Scola B, Drancourt M, Caus T, Raoult D

机构信息

Unité des Rickettsies, CNRS UMR 6020, IFR 48, Université de la Méditerranée, Faculté de Médecine, 27 boulevard Jean Moulin, 13385 Marseille cedex 05, France.

出版信息

J Clin Microbiol. 2002 May;40(5):1845-7. doi: 10.1128/JCM.40.5.1845-1847.2002.

DOI:10.1128/JCM.40.5.1845-1847.2002
PMID:11980974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC130947/
Abstract

We herein report one case of culture-negative infectious endocarditis (IE) where the organism, Granulicatella elegans, was identified by molecular analysis using broad-range PCR primers complementary to the 16S rRNA gene on the removed valve. The results and utility of this method are discussed.

摘要

我们在此报告一例血培养阴性的感染性心内膜炎（IE）病例，通过使用与切除瓣膜上16S rRNA基因互补的广谱PCR引物进行分子分析，鉴定出病原体优雅颗粒链菌。本文讨论了该方法的结果及实用性。

相似文献

1
Molecular diagnosis of Granulicatella elegans on the cardiac valve of a patient with culture-negative endocarditis.一例血培养阴性的心内膜炎患者心脏瓣膜上优雅颗粒链菌的分子诊断
J Clin Microbiol. 2002 May;40(5):1845-7. doi: 10.1128/JCM.40.5.1845-1847.2002.
2
Infective endocarditis caused by Granulicatella elegans originating in the oral cavity.由源自口腔的秀丽颗粒链菌引起的感染性心内膜炎。
J Clin Microbiol. 2005 Mar;43(3):1405-7. doi: 10.1128/JCM.43.3.1405-1407.2005.
3
Identification of Granulicatella elegans from a case of infective endocarditis, based on the phenotypic characteristics and 16S rRNA gene sequence.基于表型特征和16S rRNA基因序列，从一例感染性心内膜炎病例中鉴定出优雅颗粒链菌。
J Cardiovasc Med (Hagerstown). 2015 Jan;16 Suppl 2:S138-40. doi: 10.2459/JCM.0b013e328356a471.
4
Development of a polymerase chain reaction test for specific identification of the urinary tract pathogen Aerococcus urinae.用于特异性鉴定尿路病原体尿气球菌的聚合酶链反应检测方法的开发。
J Clin Microbiol. 1993 May;31(5):1350-3. doi: 10.1128/jcm.31.5.1350-1353.1993.
5
Molecular diagnosis of infective endocarditis by real-time broad-range polymerase chain reaction (PCR) and sequencing directly from heart valve tissue.通过实时宽范围聚合酶链反应（PCR）并直接从心脏瓣膜组织进行测序对感染性心内膜炎进行分子诊断。
Medicine (Baltimore). 2007 Jul;86(4):195-202. doi: 10.1097/MD.0b013e31811f44ec.
6
Development and evaluation of a novel fast broad-range 16S ribosomal DNA PCR and sequencing assay for diagnosis of bacterial infective endocarditis: multi-year experience in a large Canadian healthcare zone and a literature review.一种用于诊断细菌性感染性心内膜炎的新型快速宽范围16S核糖体DNA聚合酶链反应及测序检测方法的开发与评估：加拿大一个大型医疗保健区的多年经验及文献综述
BMC Infect Dis. 2016 Apr 12;16:146. doi: 10.1186/s12879-016-1476-4.
7
[An unusual case of tricuspid endocarditis by Enterococcus faecalis in native valve].[粪肠球菌引起的先天性瓣膜三尖瓣心内膜炎一例罕见病例]
Med Clin (Barc). 2003 Oct 25;121(14):559. doi: 10.1016/s0025-7753(03)74015-9.
8
The role of 16S rRNA gene sequencing in identification of microorganisms misidentified by conventional methods.16S rRNA基因测序在鉴定被传统方法误鉴定的微生物中的作用。
J Clin Microbiol. 2005 Dec;43(12):6123-5. doi: 10.1128/JCM.43.12.6123-6125.2005.
9
[Isolated tricuspid valve endocarditis as a cause of fever of unknown origin].[孤立性三尖瓣心内膜炎作为不明原因发热的一个病因]
Rev Med Liege. 2007 Nov;62(11):654-8.
10
Development of broad-range polymerase chain reaction (PCR) bacterial identification in diagnosis of infective endocarditis.
J Heart Valve Dis. 2002 Nov;11(6):870-4.

引用本文的文献

1
infections: Comprehensive review of an elusive opportunistic pathogen.感染：对一种难以捉摸的机会性病原体的全面综述。
World J Clin Cases. 2025 Oct 16;13(29):110965. doi: 10.12998/wjcc.v13.i29.110965.
2
Challenges in the diagnosis and management of endocarditis in a 9-year-old child.一名9岁儿童心内膜炎诊断与治疗中的挑战
BMJ Case Rep. 2021 Feb 18;14(2):e240079. doi: 10.1136/bcr-2020-240079.
3
Infective endocarditis due to presenting with musculoskeletal symptoms.因……导致的感染性心内膜炎伴肌肉骨骼症状。 （原句表述不完整，翻译出来的内容也不太能独立表意，推测可能有信息缺失）
BMJ Case Rep. 2019 Aug 28;12(8):e229294. doi: 10.1136/bcr-2019-229294.
4
Antimicrobial Susceptibilities of Oral Isolates of and According to the Consensus Guidelines for Fastidious Bacteria.根据苛养菌共识指南对[具体细菌名称]口腔分离株的抗菌药敏情况 。 你原文中“ and ”之间应该有具体的细菌名称，请补充完整以便更准确翻译。
Medicines (Basel). 2018 Dec 3;5(4):129. doi: 10.3390/medicines5040129.
5
A broad-range PCR technique for the diagnosis of infective endocarditis.一种用于诊断感染性心内膜炎的广谱聚合酶链反应技术。
Braz J Microbiol. 2018 Jul-Sep;49(3):534-543. doi: 10.1016/j.bjm.2017.03.019. Epub 2018 Feb 9.
6
First case of prosthetic knee infection with in the United States.美国首例伴有[具体情况未提及]的人工膝关节感染病例。
IDCases. 2017 Sep 1;10:63-64. doi: 10.1016/j.idcr.2017.08.003. eCollection 2017.
7
An unusual case of thoracic empyema caused by (nutritionally variant streptococci) in a patient with pulmonary tuberculosis and human immunodeficiency virus infection.一名患有肺结核和人类免疫缺陷病毒感染的患者发生了由（营养变异链球菌）引起的罕见胸腔积脓病例。
JMM Case Rep. 2016 Oct 27;3(5):e005058. doi: 10.1099/jmmcr.0.005058. eCollection 2016 Oct.
8
Successful treatment of periprosthetic joint infection caused by Granulicatella para-adiacens with prosthesis retention: a case report.保留假体成功治疗近平滑颗粒菌引起的人工关节周围感染：1例报告
BMC Musculoskelet Disord. 2016 Apr 12;17:156. doi: 10.1186/s12891-016-1008-9.
9
Granulicatella elegans endocarditis: a diagnostic and therapeutic challenge.秀丽颗粒链菌心内膜炎：诊断与治疗挑战
BMJ Case Rep. 2016 Feb 26;2016:bcr2015213987. doi: 10.1136/bcr-2015-213987.
10
Antimicrobial Susceptibilities of Abiotrophia defectiva, Granulicatella adiacens, and Granulicatella elegans.缺陷乏养菌、毗邻颗粒链菌和优美颗粒链菌的药敏性
Antimicrob Agents Chemother. 2015 Dec 14;60(3):1411-20. doi: 10.1128/AAC.02645-15.

本文引用的文献

1
Spontaneous development of L forms of streptococci requiring secretions of other bacteria or sulphydryl compounds for normal growth.链球菌L型的自发形成需要其他细菌的分泌物或巯基化合物才能正常生长。
Nature. 1961 Aug 12;191:728-30. doi: 10.1038/191728a0.
2
Molecular diagnosis of infective endocarditis--a new Duke's criterion.感染性心内膜炎的分子诊断——一种新的杜克标准。
Scand J Infect Dis. 2001;33(9):673-80. doi: 10.1080/00365540110026764.
3
Granulicatella and Abiotrophia species from human clinical specimens.来自人类临床标本的颗粒卡特菌属和营养缺陷菌属菌种。
J Clin Microbiol. 2001 Oct;39(10):3520-3. doi: 10.1128/JCM.39.10.3520-3523.2001.
4
Endocarditis due to rare and fastidious bacteria.由罕见且苛求菌引起的心内膜炎。
Clin Microbiol Rev. 2001 Jan;14(1):177-207. doi: 10.1128/CMR.14.1.177-207.2001.
5
Nonculture Laboratory Methods for the Diagnosis of Infectious Endocarditis.用于诊断感染性心内膜炎的非培养实验室方法。
Curr Infect Dis Rep. 1999 Jun;1(2):136-141. doi: 10.1007/s11908-996-0020-x.
6
The genus Abiotrophia (Kawamura et al.) is not monophyletic: proposal of Granulicatella gen. nov., Granulicatella adiacens comb. nov., Granulicatella elegans comb. nov. and Granulicatella balaenopterae comb. nov.阿比奥罗菲亚属（河村等人）并非单系类群：提议设立颗粒卡特拉属新属，相邻颗粒卡特拉新组合，秀丽颗粒卡特拉新组合和须鲸颗粒卡特拉新组合。
Int J Syst Evol Microbiol. 2000 Jan;50 Pt 1:365-369. doi: 10.1099/00207713-50-1-365.
7
Genetic heterogeneities and phenotypic characteristics of strains of the genus Abiotrophia and proposal of Abiotrophia para-adiacens sp. nov.阿比奥罗菲亚属菌株的遗传异质性和表型特征以及近邻阿比奥罗菲亚新种的提议
J Clin Microbiol. 2000 Feb;38(2):492-8. doi: 10.1128/JCM.38.2.492-498.2000.
8
PCR for detection and identification of Abiotrophia spp.用于检测和鉴定营养缺陷菌属的聚合酶链反应
J Clin Microbiol. 1998 Oct;36(10):2844-6. doi: 10.1128/JCM.36.10.2844-2846.1998.
9
Abiotrophia elegans sp. nov., a possible pathogen in patients with culture-negative endocarditis.秀丽乏养菌新种，一种可能导致血培养阴性的心内膜炎患者发病的病原体。
J Clin Microbiol. 1998 Jan;36(1):100-4. doi: 10.1128/JCM.36.1.100-104.1998.
10
Molecular diagnosis of bacterial endocarditis by broad-range PCR amplification and direct sequencing.通过广谱PCR扩增和直接测序对细菌性心内膜炎进行分子诊断。
J Clin Microbiol. 1997 Nov;35(11):2733-9. doi: 10.1128/jcm.35.11.2733-2739.1997.