Marx George, Seidman Ernest G, Martin Steven R, Deslandres Colette
Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Sainte-Justine Hospital, University of Montreal, Montreal, Québec, Canada.
J Pediatr. 2002 Apr;140(4):470-3. doi: 10.1067/mpd.2002.123281.
We describe the course of 7 patients younger than 2 years with Crohn's disease. Prolonged remission was achieved medically (5) or surgically (1), whereas one patient died of disseminated adenovirus. Three had malnutrition and growth failure. Crohn's disease very early in life does not always imply a poor prognosis; however, significant morbidity and mortality are encountered.
我们描述了7例2岁以下克罗恩病患儿的病程。5例经药物治疗、1例经手术治疗后实现了长期缓解,而1例患儿死于播散性腺病毒感染。3例存在营养不良和生长发育迟缓。克罗恩病在生命早期发病并不总是意味着预后不良;然而,仍会出现显著的发病率和死亡率。