Githiori John B, Höglund Johan, Waller Peter J, Baker R Leyden
International Livestock Research Institute (ILRI), PO Box 30709, Nairobi, Kenya.
J Ethnopharmacol. 2002 May;80(2-3):187-91. doi: 10.1016/s0378-8741(02)00030-2.
Myrsine africana L. and Rapanea melanophloeos L. belong to the plant family Myrsinaceae. Various rural communities in Kenya, such as smallholder farmers and pastoralists, use them to treat their livestock. The anthelmintic effects/activities of leaves and fruits of M. africana and fruits of R. melanophloeos were tested in sheep experimentally infected with the nematode parasite Haemonchus contortus. Male lambs were infected with 3000-5000 third stage larvae of H. contortus and treated 28 days after inoculation with concoctions made from leaves or fruits of the plants. No significant reduction in faecal nematode egg counts was observed with any of the concoctions at any of the doses tested. Packed red cell volume decreased and live weight increased at similar rates in treated and control groups, thus there was no significant effect of treatment. The results showed that the tested extracts of the M. africana and R. melanophloeos were not efficacious against H. contortus in sheep.
非洲铁仔（Myrsine africana L.）和黑铁木（Rapanea melanophloeos L.）属于紫金牛科植物。肯尼亚的各个农村社区，如小农户和牧民，用它们来治疗牲畜。在实验感染了线虫寄生虫捻转血矛线虫（Haemonchus contortus）的绵羊中，测试了非洲铁仔的叶子和果实以及黑铁木的果实的驱虫效果/活性。雄性羔羊感染3000 - 5000条捻转血矛线虫的第三期幼虫，并在接种后28天用由植物的叶子或果实制成的混合物进行治疗。在任何测试剂量下，任何一种混合物均未观察到粪便中线虫卵计数有显著减少。治疗组和对照组的红细胞压积以相似的速率下降，体重以相似的速率增加，因此治疗没有显著效果。结果表明，测试的非洲铁仔和黑铁木提取物对绵羊体内的捻转血矛线虫没有疗效。
