Andersen Per Kragh, Keiding Niels
Department of Biostatistics, University of Copenhagen, Danish Epidemiology Science Centre, Copenhagen, Denmark.
Stat Methods Med Res. 2002 Apr;11(2):91-115. doi: 10.1191/0962280202SM276ra.
An introduction to event history analysis via multi-state models in given. Examples include the two-state model for survival analysis, the competing risks and illness-death models, and models for bone marrow transplantation. Statistical model specification via transition intensities and likelihood inference is introduced. Consequences of observational patterns are discussed, and a real example concerning mortality and bleeding episodes in a liver cirrhosis trial is discussed.
本文介绍了通过多状态模型进行事件史分析。示例包括生存分析的两状态模型、竞争风险和疾病-死亡模型以及骨髓移植模型。介绍了通过转移强度和似然推断进行统计模型设定。讨论了观察模式的结果，并讨论了一个关于肝硬化试验中死亡率和出血事件的实际例子。
