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[神经科患者的吞咽障碍。一项关于诊断、损伤模式、治疗及预后的前瞻性研究]

[Deglutition disorders in neurological patients. A prospective study of diagnosis, pattern of impairment, therapy and outcome].

作者信息

Prosiegel M, Heintze M, Wagner-Sonntag E, Hannig C, Wuttge-Hannig A, Yassouridis A

机构信息

Neurologisches Krankenhaus München, Tristanstrasse 20, 80804 München.

出版信息

Nervenarzt. 2002 Apr;73(4):364-70. doi: 10.1007/s00115-002-1284-5.

Abstract

We performed a prospective study on 208 patients with neurogenic dysphagia who were consecutively admitted for swallowing therapy over a 3-year period. The most frequent etiology was stroke (48%). Videofluoroscopic and/or fiber optic endoscopic evaluation of swallowing were performed in 204 patients. Swallowing therapy was comprised of restitution methods, compensation, and adaptation, each of which was applied in more than 80% of the patients. Mean duration of swallowing therapy was 2 months (full oral patients 1 month, patients dependent on tube feeding or tracheostomy 2.5 and 3.5 months, respectively). Fifty-five percent of the patients initially dependent on tube feeding were full oral feeders after swallowing therapy. A target variable reflecting functional feeding status showed significant improvement after swallowing therapy, also in patients with a disease duration of more than half a year, ruling out spontaneous recovery as a sole explanation of amelioration. The following variables were the main contributors to outcome prediction: functional feeding status, Barthel index, duration of disease, and degree of aspiration as shown by endoscopy.

摘要

我们对208例神经性吞咽困难患者进行了一项前瞻性研究,这些患者在3年期间连续入院接受吞咽治疗。最常见的病因是中风(48%)。204例患者进行了吞咽的视频荧光透视和/或纤维光学内镜评估。吞咽治疗包括恢复方法、代偿和适应,每种方法在超过80%的患者中应用。吞咽治疗的平均持续时间为2个月(完全经口进食患者为1个月,依赖管饲或气管切开的患者分别为2.5个月和3.5个月)。最初依赖管饲的患者中有55%在吞咽治疗后能够完全经口进食。反映功能性进食状态的目标变量在吞咽治疗后有显著改善,病程超过半年的患者也是如此,排除了自发恢复是改善的唯一解释。以下变量是结果预测的主要因素:功能性进食状态、巴氏指数、病程以及内镜检查显示的误吸程度。

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