Stein J D, Brown G C, Brown M M, Sharma S, Hollands H, Stein H D
Center for Evidence-Based Health Care Economics, Flourtown, PA 19031, USA.
J Clin Hypertens (Greenwich). 2002 May-Jun;4(3):181-8. doi: 10.1111/j.1524-6175.2002.00970.x.
The authors evaluated the self-reported quality of life in patients with systemic arterial hypertension and assessed whether clinicians and normotensive respondents from the general public appreciate the impact that hypertension has on health-related quality of life. A quality-of-life questionnaire was completed by 385 individuals: persons with hypertension (n=188), normotensive persons (n=148), and clinicians (n=49). A utility score, which represents one's self-perceived health-related quality of life, was generated for each group by using standardized time tradeoff questionnaires. Quality of life with hypertension was judged to be significantly higher according to affected individuals (mean utility score, 0.980), compared with normotensive persons (mean utility score, 0.948) and clinicians (mean utility score, 0.942), who were asked to assume that they had hypertension (p<0.0005). Clinicians and normotensive individuals tend to overemphasize the impact that hypertension has on quality of life, as compared to affected patients. The relatively low impact that hypertensive individuals indicate high blood pressure has on their quality of life may contribute to their lack of compliance with treatment regimens.
作者评估了系统性动脉高血压患者自我报告的生活质量,并评估临床医生和普通公众中的血压正常受访者是否认识到高血压对健康相关生活质量的影响。385人完成了一份生活质量问卷,其中包括高血压患者(n = 188)、血压正常者(n = 148)和临床医生(n = 49)。通过使用标准化的时间权衡问卷,为每组生成了一个代表个人自我感知的健康相关生活质量的效用分数。与血压正常者(平均效用分数0.948)和临床医生(平均效用分数0.942,他们被要求假设自己患有高血压)相比,受影响个体认为高血压患者的生活质量显著更高(平均效用分数0.980,p<0.0005)。与受影响的患者相比,临床医生和血压正常个体往往过度强调高血压对生活质量的影响。高血压患者表示高血压对其生活质量的影响相对较低,这可能导致他们不遵守治疗方案。