Wolff G, Grädel E
Eur J Intensive Care Med. 1975 Nov;1(3):99-104. doi: 10.1007/BF00571656.
In 38 patients ventilated after open-heart surgery the effect of a 20 minutes spontaneous breathing period on right atrial pressure (RAP), left atrial pressure (LAP), pulmonary artery pressure (PAP), aortic pressure (AoP), ECG and cardiac index (CI) was monitored. Arterial bloodgas analysis before and during spontaneous breathing ruled out any respiratory failure. The test period of spontaneous breathing provoked an increase in systemic and pulmonary vascular resistance. By this and by a direct aggravation of cardiac failure the work of both ventricles dropped inspite of an increase in enddiastolic ventricular pressure. If these hemodynamic effects of a spontaneous breathing test period are taken as a guide for deciding, if a patient after open-heart surgery is ready for being extubated, the need for reintubation will be extremely rare. The study encourages us to sue mechanical ventilation as an additional instrument for treating heart failure even if no respiratory failure is present.
在38例心脏直视手术后接受通气治疗的患者中,监测了20分钟自主呼吸期对右心房压(RAP)、左心房压(LAP)、肺动脉压(PAP)、主动脉压(AoP)、心电图和心脏指数(CI)的影响。自主呼吸前后的动脉血气分析排除了任何呼吸衰竭。自主呼吸测试期导致全身和肺血管阻力增加。由此以及心力衰竭的直接加重,尽管舒张末期心室压力增加,但两个心室的工作量仍下降。如果将自主呼吸测试期的这些血流动力学效应作为决定心脏直视手术后患者是否准备好拔管的指导,再次插管的需求将极为罕见。该研究鼓励我们将机械通气作为治疗心力衰竭的一种额外手段,即使不存在呼吸衰竭。