Isobe Kenichi, Kusaka Takashi, Fujikawa Yuka, Okubo Kensuke, Nagano Keiko, Yasuda Saneyuki, Kondo Masatoshi, Itoh Susumu, Hirao Konomu, Onishi Shoju
Department of Pediatrics Kagawa Medical University, 1750-1 Mikicho, Kitagun, Kagawa 761-0793, Japan.
Comp Biochem Physiol A Mol Integr Physiol. 2002 May;132(1):133-8. doi: 10.1016/s1095-6433(01)00539-6.
To investigate whether or not the mode of delivery produces differences in cerebral oxygenation, cerebral hemoglobin oxygen saturation was measured using full-spectrum near infrared spectroscopy in 26 healthy term newborn infants immediately after birth. Infants in group 1 (n=20) were delivered vaginally, and those in group 2 (n=6) by elective cesarean section. Arterial oxygen saturation in the right hand was also measured simultaneously using a pulse oximeter. Changes in arterial oxygen saturation showed no significant difference between the two groups. The mean+/-S.D. of cerebral hemoglobin oxygen saturation in group 1 increased rapidly after birth, from 29+/-17% at 2 min to 68+/-6% at 8.5 min, followed by an almost constant value (66+/-7% at 15 min). In comparison, cerebral hemoglobin oxygen saturation in group 2 also increased rapidly until 8.5 min, but after this time decreased significantly to 57+/-5% at 15 min after birth. This indicates that the mode of delivery has a marked influence on cerebral oxygenation immediately after birth.
为了研究分娩方式是否会导致脑氧合差异，我们使用全谱近红外光谱法对26名足月健康新生儿出生后即刻的脑血红蛋白氧饱和度进行了测量。第1组（n = 20）的婴儿通过阴道分娩，第2组（n = 6）的婴儿通过择期剖宫产分娩。同时使用脉搏血氧仪测量右手的动脉血氧饱和度。两组之间动脉血氧饱和度的变化没有显著差异。第1组脑血红蛋白氧饱和度的平均值±标准差在出生后迅速上升，从2分钟时的29±17%升至8.5分钟时的68±6%，随后维持在一个几乎恒定的值（15分钟时为66±7%）。相比之下，第2组脑血红蛋白氧饱和度在8.5分钟之前也迅速上升，但此后在出生后15分钟时显著下降至57±5%。这表明分娩方式对出生后即刻的脑氧合有显著影响。
